Yuan Ning, Chai Sanbao, Sun Jianbin, Liu Yufang, Xin Sixu, Ji Linong, Zhang Xiaomei
Department of Endocrinology, Peking University International Hospital, Beijing 102206, China.
Department of Endocrinology, Peking University People's Hospital, Beijing 100044, China.
Neuro Endocrinol Lett. 2018 Feb;38(8):532-536.
Pituitary abscess (PA) is a rare intrasellar infectious disease presented in less than one percent of all cases of pituitary disease.We reported a case of a 58-year-old woman with a history of type 2 diabetes (T2DM) exhibited with headaches, nasal discharge, anosmia, diabetes insipidus and hypopituitarism due to PA, she was diagnosed based on clinical presentations, endocrine examination and MRI image features. She was treated with nasal wash and antibiotic therapy without surgical intervention. She has received hormone replacement therapy for one year and her condition has gradually become stabilized. Meanwhile, the lesion of MRI image didn't become serious after one year. Conservative treatment might be an option for the patients with PA, those rejected operation or in a stable condition.
垂体脓肿（PA）是一种罕见的鞍内感染性疾病，在所有垂体疾病病例中所占比例不到1%。我们报告了一例58岁女性病例，该患者有2型糖尿病（T2DM）病史，因垂体脓肿出现头痛、流涕、嗅觉丧失、尿崩症和垂体功能减退，根据临床表现、内分泌检查和MRI图像特征进行诊断。她接受了鼻腔冲洗和抗生素治疗，未进行手术干预。她接受激素替代治疗一年，病情逐渐稳定。同时，一年后MRI图像上的病变未加重。对于垂体脓肿患者、拒绝手术或病情稳定的患者，保守治疗可能是一种选择。
