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气管髓外浆细胞瘤:一例报告并文献复习

Extramedullary plasmacytoma of the trachea: A case report and review of the literature.

作者信息

Zhang Xi, Su Lei, Ran Yu-Ge, Qie Shuai, Zhang Xin, Liu Chan, Shi Hong-Yun

机构信息

Department of Radiation Oncology, Affiliated Hospital of Hebei University, Baoding, China.

出版信息

Medicine (Baltimore). 2018 Jan;97(3):e9594. doi: 10.1097/MD.0000000000009594.

DOI:10.1097/MD.0000000000009594
PMID:29504982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5779751/
Abstract

RATIONALE

Extramedullary plasmacytomas (EMPs) are rare solitary soft tissue tumors characterized by monoclonal proliferation of plasma cells. Most lesions occur in the head and neck, but primary tracheal lesions are very rare.

PATIENT CONCERNS

In this report, we describe a case of tracheal EMP discovered in a 48-year-old man who presented with a history of progressive dyspnea.

DIAGNOSES

Computed tomography (CT) revealed a well-defined nodular mass in the posterior wall of trachea without signs of invasion of the tracheal walls. Then, a reddish mass occluding approximately 90% of the trachea was evidenced by bronchoscopic examination.

INTERVENTIONS

The patient was treated with surgery followed by adjuvant radiotherapy to achieve better local control.

OUTCOMES

After the surgery, there was immediate symptomatic relief. There was no recurrence or metastasis during a 6-month follow-up.

LESSONS

This study presents a rare case of tracheal EMP occluding approximately 90% of the lumen that was successfully managed by surgery followed by radiotherapy.

摘要

原理

髓外浆细胞瘤(EMPs)是罕见的孤立性软组织肿瘤,其特征为浆细胞的单克隆增殖。大多数病变发生在头颈部,但原发性气管病变非常罕见。

患者情况

在本报告中,我们描述了一例在一名48岁男性中发现的气管EMPs病例,该患者有进行性呼吸困难病史。

诊断

计算机断层扫描(CT)显示气管后壁有一个边界清晰的结节状肿块,无气管壁侵犯迹象。随后,支气管镜检查发现一个微红的肿块阻塞了约90%的气管。

干预措施

患者接受了手术治疗,随后进行辅助放疗以实现更好的局部控制。

结果

手术后,症状立即缓解。在6个月的随访期间未出现复发或转移。

经验教训

本研究报告了一例罕见的气管EMPs病例,该病例阻塞了约90%的管腔,通过手术及后续放疗成功治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5067/5779751/5c4ce4b38ec2/medi-97-e9594-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5067/5779751/5f510327007b/medi-97-e9594-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5067/5779751/f0ed5928e576/medi-97-e9594-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5067/5779751/d6d0ff0667ec/medi-97-e9594-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5067/5779751/5c4ce4b38ec2/medi-97-e9594-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5067/5779751/5f510327007b/medi-97-e9594-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5067/5779751/f0ed5928e576/medi-97-e9594-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5067/5779751/d6d0ff0667ec/medi-97-e9594-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5067/5779751/5c4ce4b38ec2/medi-97-e9594-g004.jpg

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Successful treatment of primary advanced gastric plasmacytoma using a combination of surgical resection and chemotherapy with bortezomib: A case report.手术切除联合硼替佐米化疗成功治疗原发性晚期胃浆细胞瘤:一例报告
Int J Surg Case Rep. 2016;27:133-136. doi: 10.1016/j.ijscr.2016.08.041. Epub 2016 Sep 3.
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Imaging of a case of extramedullary solitary plasmacytoma of the trachea.
病例报告:一例未同时诊断为多发性骨髓瘤的髓外浆细胞瘤罕见表现。
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A rare case of primary solitary endobronchial plasmacytoma.原发性孤立性支气管内浆细胞瘤 1 例罕见报告
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Retroperitoneal extramedullary plasmacytoma: A case report and review of the literature.腹膜后髓外浆细胞瘤:一例报告并文献复习
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