Medici Maria Cristina, Tummolo Fabio, Martella Vito, De Conto Flora, Arcangeletti Maria Cristina, Pinardi Federica, Ferraglia Francesca, Chezzi Carlo, Calderaro Adriana
Department of Medicine and Surgery, University of Parma, Parma, Italy.
Department of Veterinary Medicine, University Aldo Moro of Bari, Valenzano, Italy.
New Microbiol. 2018 Jan;41(1):71-72.
In the winter season 2014/15, the GII.P17_GII.17 norovirus strain Kawasaki 2014 emerged in Italy, cocirculating with pandemic GII.4 strains. In March 2016, molecular investigation identified novel GII.P16 recombinant noroviruses in children with gastroenteritis in Italy. In 43.10% of the genotyped noroviruses GII.P16 strains were identified: 12 were characterized as GII.2 and 13 as GII.4 Sydney 2012 capsid genotypes. The GII.P16 genotype became predominant in January- February 2017 along with an increase in norovirus activity. The capsid gene was characterized as GII.2 or GII.4 Sydney 2012 variant. The emergence of two different recombinant GII.P16 viruses, of which one harboring a pandemic GII.4 capsid sequence, suggests the potential for a future pandemic.
在2014/15年冬季，GII.P17_GII.17诺如病毒株“川崎2014”在意大利出现，并与大流行的GII.4毒株共同传播。2016年3月，分子调查在意大利患肠胃炎的儿童中发现了新型GII.P16重组诺如病毒。在43.10%的基因分型诺如病毒中鉴定出GII.P16毒株：12株被鉴定为GII.2基因型，13株为GII.4悉尼2012衣壳基因型。随着诺如病毒活性增加，GII.P16基因型在2017年1月至2月成为优势基因型。衣壳基因被鉴定为GII.2或GII.4悉尼2012变体。两种不同的重组GII.P16病毒的出现，其中一种含有大流行的GII.4衣壳序列，提示了未来发生大流行的可能性。
