Wengrower D, Tzfoni E E, Drenger B, Leitersdorf E
Respiration. 1986;50(4):301-3. doi: 10.1159/000194942.
Penicillin and its derivatives are known to cause several dermatologic and pulmonary hypersensitivity reactions. This report describes a patient who presented with combined generalized exfoliative dermatitis and severe pneumonitis caused by penicillin and aggravated by ampicillin, methicillin and mezlocillin. Antibiotic challenges with penicillin caused immediate reappearance of the dermatological manifestation; reactivation of the pneumonitis was probably prevented by immediate discontinuation of the drug.
已知青霉素及其衍生物会引发多种皮肤和肺部过敏反应。本报告描述了一名患者，该患者出现了由青霉素引起并因氨苄西林、甲氧西林和美洛西林而加重的全身性剥脱性皮炎和严重肺炎。用青霉素进行抗生素激发试验导致皮肤病表现立即再次出现；通过立即停药可能预防了肺炎的复发。
