Department of Surgery, Division of Abdominal Organ Transplantation, Washington University School of Medicine, St Louis, MO.
Mid America Transplant Services, St Louis, MO.
J Am Coll Surg. 2018 May;226(5):909-916. doi: 10.1016/j.jamcollsurg.2018.02.005. Epub 2018 Mar 2.
Donation after cardiac death (DCD) is one method of organ donation. Nationally, more than half of evaluated DCD donors do not yield transplantable organs. There is no algorithm for predicting which DCD donors will be appropriate for organ procurement. Donation after cardiac death program costs from an organ procurement organization (OPO) accounting for all evaluated donors have not been reported.
Hospital, transportation, and supply costs of potential DCD donors evaluated at a single OPO from January 2009 to June 2016 were collected. Mean costs per donor and per organ were calculated. Cost of DCD donors that did not yield a transplantable organ were included in cost analyses resulting in total cost of the DCD program. Donation after cardiac death donor costs were compared with costs of in-hospital donation after brain death (DBD) donors.
There were 289 organs transplanted from 264 DCD donors evaluated. Mean cost per DCD donor yielding transplantable organs was $9,306. However, 127 donors yielded no organs, at a mean cost of $8,794 per donor. The total cost of the DCD program was $32,020 per donor and $15,179 per organ. Mean cost for an in-hospital DBD donor was $33,546 and $9,478 per organ transplanted. Mean organ yield for DBD donors was 3.54 vs 2.21 for DCD donors (p < 0.0001), making the cost per DBD organ 63% of the cost of a DCD organ.
Mean cost per DCD donor is comparable with DBD donors, however, individual cost of DCD organs increases by almost 40% when all costs of an entire DCD program are included.
心脏死亡后捐献(DCD)是器官捐献的一种方式。在全国范围内,超过一半评估为 DCD 供者的器官无法用于移植。目前尚无预测哪些 DCD 供者适合进行器官获取的算法。尚未报告过一个器官获取组织(OPO)从所有评估的 DCD 供者中核算的 DCD 项目成本。
收集了 2009 年 1 月至 2016 年 6 月期间在单一 OPO 评估的潜在 DCD 供者的医院、运输和供应成本。计算了每位供者和每个器官的平均成本。将未能提供可移植器官的 DCD 供者的成本纳入成本分析中,得出 DCD 项目的总成本。将 DCD 供者的成本与院内脑死亡(DBD)供者的成本进行比较。
从 264 位评估的 DCD 供者中移植了 289 个器官。每个有可移植器官的 DCD 供者的平均成本为 9306 美元。然而,有 127 位供者没有器官,每位供者的平均成本为 8794 美元。DCD 项目的总成本为每位供者 32020 美元,每个器官 15179 美元。院内 DBD 供者的平均成本为 33546 美元,每个移植器官的成本为 9478 美元。DBD 供者的平均器官产出为 3.54 个,而 DCD 供者为 2.21 个(p<0.0001),这使得 DBD 器官的每个器官成本为 DCD 器官的 63%。
每个 DCD 供者的平均成本与 DBD 供者相当,但是,当纳入整个 DCD 项目的所有成本时,DCD 器官的单个成本增加了近 40%。