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先天性腹壁缺陷的产前诊断与管理

Prenatal diagnosis and management of congenital defects of the anterior abdominal wall.

作者信息

Sermer M, Benzie R J, Pitson L, Carr M, Skidmore M

出版信息

Am J Obstet Gynecol. 1987 Feb;156(2):308-12. doi: 10.1016/0002-9378(87)90274-2.

Abstract

Between the years 1980 and 1985, 25 cases of anterior abdominal wall defects were identified within the University of Toronto Perinatal Complex. There were 17 cases of omphalocele and eight cases of gastroschisis. Associated anomalies were found in 71% of infants with omphalocele and 50% with gastroschisis. They were the major cause of neonatal death. Prematurity was the second most common cause of death. The neonatal death rate was 59% in omphalocele and 38% in gastroschisis; the prematurity rates were 53% and 50%, respectively. In omphalocele, there was a 47% cesarean section rate, with a 50% neonatal death rate. Vaginal delivery was associated with a 67% death rate. In gastroschisis, there was a 50% cesarean section rate, with a 50% neonatal death rate. Vaginal delivery was associated with a 25% death rate. There is no evidence that cesarean section offers improved neonatal survival.

摘要

1980年至1985年间,多伦多大学围产期中心共确诊25例腹壁前部缺损病例。其中脐膨出17例,腹裂8例。71%的脐膨出婴儿和50%的腹裂婴儿伴有其他异常。这些异常是新生儿死亡的主要原因。早产是第二常见的死亡原因。脐膨出的新生儿死亡率为59%,腹裂为38%;早产率分别为53%和50%。脐膨出的剖宫产率为47%,新生儿死亡率为50%。经阴道分娩的死亡率为67%。腹裂的剖宫产率为50%,新生儿死亡率为50%。经阴道分娩的死亡率为25%。没有证据表明剖宫产能提高新生儿存活率。

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