口服多潘立酮治疗糖尿病胃轻瘫。
Treatment of diabetic gastroparesis with oral domperidone.
作者信息
Watts G F, Armitage M, Sinclair J, Hill R D
出版信息
Diabet Med. 1985 Nov;2(6):491-2. doi: 10.1111/j.1464-5491.1985.tb00689.x.
Abstract
Three patients with severe diabetic gastroparesis unresponsive to metoclopramide were found to have markedly prolonged gastric half-emptying times (t1/2) using a radionuclide-labelled test meal. They all showed symptomatic improvement and normal t1/2 within one week of taking oral domperidone 10 mg q.d.s. Oral domperidone may have a role in the treatment of severe diabetic gastroparesis particularly in metoclopramide-resistant cases.
摘要
三名对胃复安无反应的严重糖尿病胃轻瘫患者，通过放射性核素标记测试餐发现其胃半排空时间（t1/2）明显延长。他们在每日四次口服10毫克多潘立酮一周内均表现出症状改善且t1/2恢复正常。口服多潘立酮可能在严重糖尿病胃轻瘫的治疗中发挥作用，尤其是在对胃复安耐药的病例中。
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