Poletti Fabrizio, Coccino Claudio, Monolo Davide, Crespi Paolo, Ciccioli Giorgio, Cordio Giuseppe, Seveso Giovanni, De Servi Stefano
1 Cardiology Unit, Ospedale Civile di Legnano, Legnano, Italy.
2 Cardiology Unit, IRCCS Multimedica Group, Sesto San Giovanni, Italy.
J Vasc Access. 2018 Sep;19(5):455-460. doi: 10.1177/1129729818758984. Epub 2018 Mar 7.
Patients admitted to cardiac intensive care unit need administration of drugs intravenously often in concomitance of therapeutic techniques such as non-invasive ventilation, continuous renal replacement therapy and intra-aortic balloon counterpulsation. Therefore, the insertion of central venous catheters provides a reliable access for delivering medications, laboratory testing and hemodynamic monitoring, but it is associated with the risk of important complications. In our study, we tested the efficacy and safety of peripherally inserted central catheters to manage cardiac intensive care.
All patients admitted to cardiac intensive care unit with indication for elective central venous access were checked by venous arm ultrasound for peripherally inserted central catheter's implantation. Peripherally inserted central catheters were inserted by ultrasound-guided puncture. After 7 days from the catheter's placement and at the removal, vascular ultrasound examination was performed searching signs of upper extremity deep venous thrombosis. In case of sepsis, blood cultures peripherally from the catheter and direct culture of the tip of the catheter were done to establish a catheter-related blood stream infection.
In our cardiac intensive care unit, 137 peripherally inserted central catheters were placed: 80.3% of patients eligible for a peripherally inserted central catheter were implanted. The rate of symptomatic catheter-related peripheral venous thrombosis was 1.4%. Catheter-related blood stream infection was diagnosed in one patient (0.7%; 5.7 × 1000 peripherally inserted central catheter days). All peripherally inserted central catheters were inserted successfully without other major complications.
In patients admitted to cardiac intensive care unit, peripherally inserted central catheters' insertion was feasible in a high percentage of patients and was associated with low infective complications and clinical thrombosis rate.
入住心脏重症监护病房的患者通常需要静脉给药,同时还需要进行无创通气、持续肾脏替代治疗和主动脉内球囊反搏等治疗技术。因此,中心静脉导管的插入为给药、实验室检测和血流动力学监测提供了可靠的途径,但它也伴随着重要并发症的风险。在我们的研究中,我们测试了经外周静脉穿刺中心静脉导管用于心脏重症监护的有效性和安全性。
所有入住心脏重症监护病房且有择期中心静脉置管指征的患者,均通过上肢静脉超声检查以确定是否适合植入经外周静脉穿刺中心静脉导管。经外周静脉穿刺中心静脉导管通过超声引导穿刺插入。在导管置入7天后及拔除时,进行血管超声检查以寻找上肢深静脉血栓形成的迹象。如发生败血症,从导管外周采集血培养样本,并对导管尖端进行直接培养,以确定是否存在导管相关血流感染。
在我们的心脏重症监护病房,共置入了137根经外周静脉穿刺中心静脉导管:符合经外周静脉穿刺中心静脉导管置入条件的患者中有80.3%成功植入。有症状的导管相关外周静脉血栓形成率为1.4%。一名患者被诊断为导管相关血流感染(0.7%;每1000个经外周静脉穿刺中心静脉导管日中有5.7例)。所有经外周静脉穿刺中心静脉导管均成功插入,无其他重大并发症。
对于入住心脏重症监护病房的患者,经外周静脉穿刺中心静脉导管的插入在大多数患者中是可行的,且感染并发症和临床血栓形成率较低。