Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Gyeonggi, South Korea.
Department of Orthopaedic Surgery, SMG‑SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, South Korea.
PLoS One. 2018 Mar 8;13(3):e0192478. doi: 10.1371/journal.pone.0192478. eCollection 2018.
This study was performed to investigate the factors associated with the level of knee pain in a nationally representative sample of noninstitutionalized women aged 50 years or older.
Women aged 50 years or older were selected and included in the data analyses from the Korean National Health and Nutrition Examination Surveys (2010-2013). Those having malignant diseases or using osteoarthritis medication were excluded. Significant factors associated with the level of knee pain were analyzed using multivariate regression analysis.
A total of 5148 women (average age, 62.9 years; standard deviation, 9.3 years) were included. For women without knee osteoarthritis, level of hip pain (p<0.001), presence of back pain (p<0.001), age (p<0.001), and body mass index (BMI) (p<0.001) were found to be significant factors associated with the level of knee pain. For women with knee osteoarthritis, the radiographic grade of knee osteoarthritis (p<0.001), presence of back pain (p<0.001), level of hip pain (p<0.001), presence of depressive symptoms (p<0.001), and BMI (p = 0.026) were the factors significantly associated with the level of knee pain.
Women without knee osteoarthritis tended to report increasing knee pain with increasing age. BMI is considered a significant controllable factor in knee pain in women regardless of the presence of radiographic knee osteoarthritis. The presence of depressive symptoms may aggravate knee pain in women with knee osteoarthritis. Attention needs to be focused on concomitant musculoskeletal problems such as lumbar spinal and hip diseases in women with knee pain.
本研究旨在调查与 50 岁及以上非住院女性膝关节疼痛程度相关的因素。
选择年龄在 50 岁及以上的女性，并纳入韩国国家健康和营养检查调查（2010-2013 年）的数据分析。排除患有恶性疾病或使用骨关节炎药物的患者。使用多元回归分析来分析与膝关节疼痛程度相关的显著因素。
共纳入 5148 名女性（平均年龄 62.9 岁，标准差 9.3 岁）。对于没有膝关节骨关节炎的女性，髋关节疼痛程度（p<0.001）、背痛（p<0.001）、年龄（p<0.001）和体重指数（BMI）（p<0.001）是与膝关节疼痛程度相关的显著因素。对于患有膝关节骨关节炎的女性，膝关节骨关节炎的放射学分级（p<0.001）、背痛（p<0.001）、髋关节疼痛程度（p<0.001）、抑郁症状（p<0.001）和 BMI（p=0.026）是与膝关节疼痛程度相关的显著因素。
没有膝关节骨关节炎的女性随着年龄的增长往往会报告膝关节疼痛加剧。BMI 是无论是否存在放射学膝关节骨关节炎，女性膝关节疼痛的一个重要可控因素。抑郁症状的存在可能会加重膝关节骨关节炎女性的膝关节疼痛。需要关注膝关节疼痛女性同时存在的骨骼肌肉问题，如腰椎脊柱和髋关节疾病。
