Cecere L, Funaro G, De Cataldis G, Carnicelli P, Pinto R
Respiration. 1986;50 Suppl 2:245-8. doi: 10.1159/000195137.
Twelve patients, aged over 60 years and suffering from chronic obstructive lung disease, were treated for 12 weeks with Duovent (fenoterol + ipratropium bromide). The clinical check-ups and indices of bronchial obstruction (FEV1, VC, RV, sGaw) were performed every 14 days. Improvement in symptoms corresponded to a significant improvement in the functional parameters. No negative cardiovascular effects, significant side-effects, or tolerance were seen after drug administration.
12名年龄超过60岁且患有慢性阻塞性肺疾病的患者接受了12周的多索茶碱（非诺特罗+异丙托溴铵）治疗。每14天进行一次临床检查和支气管阻塞指标（第一秒用力呼气容积、肺活量、残气量、比气道传导率）的检测。症状的改善与功能参数的显著改善相对应。给药后未观察到负面心血管效应、显著副作用或耐受性问题。
