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哮喘患者宿主防御系统的评估。

Evaluation of the host defense system in asthmatic patients.

作者信息

Grassi G G, Zanon P, Fietta A, De Rose V, Mangiarotti P, Grassi C

出版信息

Respiration. 1986;50 Suppl 2:83-91. doi: 10.1159/000195105.

DOI:10.1159/000195105
PMID:2951829
Abstract

The efficiency of some components of the host defense system has been evaluated in 32 atopic patients with rhinitis, asthma or asthma and rhinitis. No alterations in components of complement (C3 and C4), serum immunoglobulins (IgG, IgA, and IgM) and neutrophil functional parameters were found. As expected, serum IgE values were higher than in controls. A decreased percentage of total circulating T lymphocytes, an increased percentage of Ia1-positive cells, but normal values of OKT4- and OKT8-positive T lymphocytes were demonstrated. However, a greater heterogeneity in the distribution of the suppressor-cytotoxic subset was shown in atopic patients.

摘要

在32例患有鼻炎、哮喘或哮喘合并鼻炎的特应性患者中评估了宿主防御系统某些成分的效率。未发现补体成分(C3和C4)、血清免疫球蛋白(IgG、IgA和IgM)及中性粒细胞功能参数有改变。正如预期的那样,血清IgE值高于对照组。总循环T淋巴细胞百分比降低,Ia1阳性细胞百分比增加,但OKT4和OKT8阳性T淋巴细胞值正常。然而,特应性患者中抑制性细胞毒性亚群的分布存在更大的异质性。

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