Secombe P J, Sutherland R, Johnson R
Intensive Care Consultant, Alice Springs Hospital; Clinical Lecturer, School of Medicine, Flinders University; Alice Springs, Northern Territory.
Advanced Trainee in Emergency Medicine, Member of the Australasian College for Emergency Medicine; Flinders Medical Centre, Adelaide, South Australia.
Anaesth Intensive Care. 2018 Mar;46(2):171-177. doi: 10.1177/0310057X1804600205.
Adequate cardiopulmonary resuscitation is an important predictor of survival, however, obesity provides a significant physical barrier to thoracic compressions. This study explores the effect of morbid obesity on compression adequacy. We performed a prospective randomised controlled crossover study, assessing the adequacy of thoracic compressions on a manikin modified to emulate a morbidly obese patient. Participants recruited from critical care departments were randomised to perform continuous compressions for two minutes on each manikin. Accelerometers were used to measure thoracic wall movement. The primary endpoint was a composite measure of compression adequacy (rate, depth and recoil). Secondary endpoints were the individual components of the composite outcome and measures of perceived effectiveness, fatigue, and pain. One hundred and one participants were recruited. There was a significant difference between the obese and control groups in the composite endpoint (4% versus 30%, <0.001), as well as the individual components of adequacy ( <0.01 for all). Quartile data showed significant deterioration in adequacy of depth and recoil in both groups, and this occurred significantly earlier in the obese group ( ≤0.001). Participants' perception of effectiveness was significantly lower ( ≤0.001) in the obese group, and levels of fatigue ( ≤0.001) and pain ( ≤0.001) significantly higher. Morbid obesity impairs the adequacy of thoracic compressions for trained rescuers in a simulation-based model. Participants were not fully aware of how ineffective compressions were. There is evidence of earlier fatigue further reducing effectiveness. These findings have significant implications for the training of rescuers in a clinically relevant population and the planning of future research.
充分的心肺复苏是生存的重要预测指标,然而,肥胖为胸外按压带来了巨大的身体障碍。本研究探讨病态肥胖对按压充分性的影响。我们进行了一项前瞻性随机对照交叉研究,在一个经改良以模拟病态肥胖患者的人体模型上评估胸外按压的充分性。从重症监护病房招募的参与者被随机分配在每个模型上进行两分钟的持续按压。使用加速度计测量胸壁运动。主要终点是按压充分性的综合指标(速率、深度和回弹)。次要终点是综合结果的各个组成部分以及感知效果、疲劳和疼痛的指标。共招募了101名参与者。肥胖组和对照组在综合终点方面存在显著差异(4%对30%,<0.001),在充分性的各个组成部分方面也存在显著差异(所有均<0.01)。四分位数数据显示两组深度和回弹的充分性均显著恶化,且肥胖组出现得更早(≤0.001)。肥胖组参与者对效果的感知显著更低(≤0.001),疲劳程度(≤0.001)和疼痛程度(≤0.001)显著更高。在基于模拟的模型中,病态肥胖会损害训练有素的救援人员胸外按压的充分性。参与者并未充分意识到按压效果有多差。有证据表明更早出现的疲劳会进一步降低效果。这些发现对临床相关人群中救援人员的培训以及未来研究的规划具有重要意义。