Adachi Tadashi, Wada-Isoe Kenji
Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University.
Brain Nerve. 2018 Mar;70(3):211-220. doi: 10.11477/mf.1416200983.
We provide a general overview of pharmacologic treatments for different types of dementia in light of the Guidelines on the Clinical Management of Dementia in Japan 2017, clinical data not addressed in those guidelines, and the results of observational studies, focusing mainly on the treatment of Alzheimer-type dementia. In everyday clinical practice, patients must be provided with personalized treatment that strikes a balance between evidence-based treatment, as described in the guidelines and actual clinical circumstances.
我们依据《2017年日本痴呆症临床管理指南》、该指南未涉及的临床数据以及观察性研究结果,对不同类型痴呆症的药物治疗进行了概述,主要聚焦于阿尔茨海默型痴呆症的治疗。在日常临床实践中,必须为患者提供个性化治疗,在指南中所述的循证治疗与实际临床情况之间取得平衡。