Dolgun Z N, Inan C, Altintas A S, Okten S B, Karadag C, Sayin N C
Department of Obstetrics and Gynecology, Trakya University Medicine Faculty, Edirne, Turkey.
Department of Obstetrics and Gynecology, Pendik Research and Education Hospital, Marmara University, Istanbul, Turkey.
Niger J Clin Pract. 2018 Mar;21(3):312-317. doi: 10.4103/njcp.njcp_333_16.
Preterm birth is one of the most challenging problems in obstetric care and it is closely related to perinatal mortality and morbidity. The aim of the current study was to document our experience with preterm births and to analyze the association between perinatal variables and clinical outcomes.
In this retrospective study, data were derived from the medical records of 785 singleton preterm births delivered in the obstetrics and gynecology department of our institution. Variables under investigation were maternal and gestational ages, fetal gender, route of delivery (vaginal vs. cesarean section [C/S]), causes of preterm birth, birth weight, placental weight, umbilical cord length, and Apgar scores at the 1 and 5 min.
Pregnant women with advanced age (≥35 years) were more likely to undergo C/S (P < 0.001). Apgar score at the 1 and 5 min was influenced significantly by gestational age (P < 0.001), newborn birth weight (P < 0.001), placental weight (P < 0.001), and umbilical cord length (P < 0.001). Infants delivered due to antepartum fetal distress indication had remarkably lower Apgar scores at the 1 min and the birth weight seemed to be positively correlated with Apgar scores at both 1 (P < 0.001) and 5 min (P < 0.001). Apgar scores both at the 1 and 5 min were positively correlated with placental weight (R: 0.239 and 0.231, respectively, and P < 0.001 for both) and length of umbilical cord (R:0.228 and 0.211, respectively, and P < 0.001 for both).
Advanced age pregnancies have higher C/S rates, but Apgar scores are significantly correlated with infant characteristics. Umbilical cord length and placental weight might be the new add-on predictors of postpartum well-being in premature infants.
早产是产科护理中最具挑战性的问题之一,与围产期死亡率和发病率密切相关。本研究的目的是记录我们在早产方面的经验,并分析围产期变量与临床结局之间的关联。
在这项回顾性研究中,数据来自于我们机构妇产科分娩的785例单胎早产的病历。研究的变量包括产妇年龄和孕周、胎儿性别、分娩方式(阴道分娩与剖宫产[C/S])、早产原因、出生体重、胎盘重量、脐带长度以及1分钟和5分钟时的阿氏评分。
高龄(≥35岁)孕妇更有可能接受剖宫产(P < 0.001)。1分钟和5分钟时的阿氏评分受孕周(P < 0.001)、新生儿出生体重(P < 0.001)、胎盘重量(P < 0.001)和脐带长度(P < 0.001)的显著影响。因产前胎儿窘迫指征分娩的婴儿1分钟时阿氏评分显著较低,出生体重似乎与1分钟(P < 0.001)和5分钟(P < 0.001)时的阿氏评分呈正相关。1分钟和5分钟时的阿氏评分均与胎盘重量(分别为R:0.239和0.231,两者P均< 0.001)和脐带长度(分别为R:0.228和0.211,两者P均< 0.001)呈正相关。
高龄妊娠剖宫产率较高,但阿氏评分与婴儿特征显著相关。脐带长度和胎盘重量可能是早产儿产后健康的新附加预测指标。