Murphy J D, Sands B L, Norwood W I
Am J Cardiol. 1987 Apr 15;59(9):949-51. doi: 10.1016/0002-9149(87)91131-3.
During a 1-year period, 9 children, aged 3 to 18 months, underwent intraoperative transluminal balloon angioplasty of coarctation of the aorta. Each patient had previously undergone palliative surgery for hypoplastic left heart syndrome. In 1 patient the angioplasty catheter was introduced into the ascending aorta during surgery to correct intracardiac defects. In the other 8 infants the catheters were inserted directly into the descending thoracic aorta via thoracotomy because the catheter size precluded percutaneous insertion into the femoral artery. In each case, after measuring the systolic pressure gradient across the coarctation, the angioplasty catheters were advanced over the guidewire across the coarctation site. The balloons were then inflated 2 to 3 times with an internal pressure of 3 to 6 atm. After the dilation sequence the angioplasty catheters were removed and the pressures were again measured above and below the coarctation. Preoperative gradients across the coarctation site ranged from 26 to 85 mm Hg (mean 45). Immediately after the procedure the gradient decreased in each case, ranging from 0 to 12 mm Hg (mean 4.3). There were no signs of disruption of the aortic wall. Relief of the pressure gradient persisted in the 7 patients who underwent follow-up cardiac catheterization after the procedure. The patients have been followed for as long as 18 months after the procedure and none has shown physical or echocardiographic evidence of recurrent aortic obstruction.(ABSTRACT TRUNCATED AT 250 WORDS)
在1年的时间里,9名年龄在3至18个月的儿童接受了主动脉缩窄的术中经腔球囊血管成形术。每名患者此前都因左心发育不全综合征接受过姑息性手术。1例患者在手术中为纠正心内缺损,将血管成形术导管插入升主动脉。其他8例婴儿因导管尺寸过大无法经皮插入股动脉,故通过开胸术将导管直接插入降主动脉。在每种情况下,测量缩窄部位的收缩压梯度后,将血管成形术导管沿导丝推进穿过缩窄部位。然后以3至6个大气压的内部压力将球囊充气2至3次。扩张步骤完成后,取出血管成形术导管,再次测量缩窄部位上方和下方的压力。术前缩窄部位的梯度范围为26至85毫米汞柱(平均45)。术后每种情况的梯度均下降,范围为0至12毫米汞柱(平均4.3)。没有主动脉壁破裂的迹象。在术后接受随访心脏导管检查的7例患者中,压力梯度持续缓解。术后对患者进行了长达18个月的随访,无一例出现主动脉再梗阻的体格检查或超声心动图证据。(摘要截短至250字)