Zambelis Thomas, Koutsoudaki Pinelopi, Anagnostou Evangelos, Kokotis Panagiotis, Karandreas Nikolaos
Department of Neurology, National and Kapodistrian University of Athens, Aeghinition Hospital, Athens, Greece.
J Clin Neurophysiol. 2018 May;35(3):267-269. doi: 10.1097/WNP.0000000000000465.
The aim of our study was the comparison of active denervation (fibrillation and/or positive sharp wave potentials) in thoracic paraspinal muscles with rectus abdominis in patients with definite amyotrophic lateral sclerosis.
Ninety-five consecutive patients with clinically definite amyotrophic lateral sclerosis according to the revised El Escorial criteria were studied prospectively over a 5-year period. Concentric needle electromyogram was performed in thoracic paraspinal muscles, in the rectus abdominis at the T9 level, and in limb muscles.
Active denervation was present in thoracic paraspinal muscles in 75 patients (79%) and in rectus abdominis in 62 patients (65.3%) (P = 0.02). No significant difference was found between the two muscles regarding the type of onset (bulbar, upper, and lower limbs), amyotrophic lateral sclerosis functional rating scale values, and creatine phosphokinase levels.
Thoracic paraspinal muscles are the first to be tested in patients with amyotrophic lateral sclerosis. Absence of active denervation in T-PSM is rarely associated with active denervation in rectus abdominis.
我们研究的目的是比较明确诊断为肌萎缩侧索硬化症患者的胸段椎旁肌与腹直肌的主动失神经支配（纤颤和/或正锐波电位）情况。
根据修订的埃尔埃斯科里亚尔标准，对95例临床确诊为肌萎缩侧索硬化症的患者进行了为期5年的前瞻性研究。对胸段椎旁肌、T9水平的腹直肌以及肢体肌肉进行了同心针电极肌电图检查。
75例患者（79%）的胸段椎旁肌存在主动失神经支配，62例患者（65.3%）的腹直肌存在主动失神经支配（P = 0.02）。在发病类型（延髓、上肢和下肢）、肌萎缩侧索硬化功能评定量表值以及肌酸磷酸激酶水平方面，两块肌肉之间未发现显著差异。
胸段椎旁肌是肌萎缩侧索硬化症患者首先要检查的部位。胸段椎旁肌无主动失神经支配很少与腹直肌的主动失神经支配相关。
