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[1.5特斯拉核磁共振波谱法对肾上腺皮质病变中脂质/水比例变化的显示]

[Demonstration by spectroscopy NMR at 1,5 Tesla of changes in lipid/water ratio in pathology of the adrenal cortex].

作者信息

Roucayrol J C, Leroy-Willig A, Courtieu J, Luton J P

出版信息

C R Seances Soc Biol Fil. 1986;180(6):677-82.

PMID:2952229
Abstract

By NMR proton spectrometry with a main field of approximately 1.5 Tesla the authors have studied on pieces obtained at surgery changes of the lipid/water ratio in the cortex of diseased adrenal glands. On the basis of 58 samples taken from 20 different glands they show that this ratio is comparable in hyperplasias and adenomas but quite significantly reduced in carcinomas. They are therefore of the opinion that this ratio might serve as a malignancy index in spectroscopic imaging of patients bearing tumors of the adrenal cortex.

摘要

通过使用主磁场约为1.5特斯拉的核磁共振质子光谱法,作者对手术获取的病变肾上腺皮质样本的脂质/水比例变化进行了研究。基于从20个不同腺体采集的58个样本,他们发现该比例在增生和腺瘤中相当,而在癌中则显著降低。因此,他们认为该比例可作为肾上腺皮质肿瘤患者光谱成像中的恶性指标。

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