Chang Edward T, Baik Grace, Torre Carlos, Brietzke Scott E, Camacho Macario
Department of Surgery, Division of Otolaryngology, Tripler Army Medical Center, 1 Jarrett White Road, Honolulu, HI, 96859, USA.
Department of Otolaryngology-Head and Neck Surgery, Walter Reed National Military Medical Center, 8901 Rockville Pike, Bethesda, MD, 20889, USA.
Sleep Breath. 2018 Dec;22(4):955-961. doi: 10.1007/s11325-018-1651-5. Epub 2018 Mar 9.
Currently, the relationship between uvula size and sleep-disordered breathing (snoring and obstructive sleep apnea) lacks data for objective interpretation. This study conducted a systematic review of the international literature for research describing the measurable characteristics of the uvula (i.e., size, length, width) and any association with snoring and obstructive sleep apnea (OSA). PubMED, Scopus, Google Scholar, Embase, and the Cochrane Library were each systematically searched from inception through November 15, 2016. We screened 1037 titles and abstracts. We conducted a full review of 54 downloaded articles. Sixteen articles met inclusion and exclusion criteria. The 16 studies included a total of 2604 patients. The selected articles included data and information for (1) normative data for uvular size in the control groups, (2) snoring and uvula size, (3) OSA and uvula size, and (4) overall uvula function. Our review noted variability in findings; however, in general, a uvular length > 15 mm was considered elongated and a uvular width > 10 mm was considered to be wide. The studies included in this systematic review reveal a relationship between uvula size, snoring, and OSA. Further, larger uvulas appear associated with more severe snoring and OSA. The direct correlation between uvula size and its relationship specifically to snoring and OSA remain as topics for future prospective research.
目前，悬雍垂大小与睡眠呼吸紊乱（打鼾和阻塞性睡眠呼吸暂停）之间的关系缺乏可供客观解读的数据。本研究对国际文献进行了系统综述，以查找描述悬雍垂可测量特征（即大小、长度、宽度）以及与打鼾和阻塞性睡眠呼吸暂停（OSA）之间任何关联的研究。分别从创刊至2016年11月15日对PubMed、Scopus、谷歌学术、Embase和考科蓝图书馆进行了系统检索。我们筛选了1037篇标题和摘要。对下载的54篇文章进行了全面审查。16篇文章符合纳入和排除标准。这16项研究共纳入2604例患者。所选文章包含以下方面的数据和信息：（1）对照组悬雍垂大小的规范数据，（2）打鼾与悬雍垂大小，（3）OSA与悬雍垂大小，以及（4）悬雍垂的整体功能。我们的综述注意到研究结果存在差异；然而，一般来说，悬雍垂长度>15mm被认为过长，悬雍垂宽度>10mm被认为过宽。本系统综述纳入的研究揭示了悬雍垂大小、打鼾和OSA之间的关系。此外，较大的悬雍垂似乎与更严重的打鼾和OSA相关。悬雍垂大小与其与打鼾和OSA的关系之间的直接相关性仍是未来前瞻性研究的课题。
