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使用睡眠荧光透视法评估阻塞性睡眠呼吸暂停患者的软腭变化。

Evaluation of soft palate changes using sleep videofluoroscopy in patients with obstructive sleep apnea.

作者信息

Lee Chul Hee, Mo Ji-Hun, Kim Bong Jik, Kong Il Gyu, Yoon In Young, Chung Seockhoon, Kim Jae-Hyung, Kim Jeong-Whun

机构信息

Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 300 Gumi-dong Bundang-gu, Seongnam-si, Gyeonggi-do 464-707, South Korea.

出版信息

Arch Otolaryngol Head Neck Surg. 2009 Feb;135(2):168-72. doi: 10.1001/archoto.2008.538.

Abstract

OBJECTIVE

To quantitatively evaluate the changes in the soft palate (SP) by sleep videofluoroscopy (SVF).

DESIGN

Retrospective analysis.

SETTING

Academic tertiary referral center.

PATIENTS

A total of 63 consecutive patients with snoring or sleep apnea (53 with obstructive sleep apnea [OSA] and 10 simple snorers).

INTERVENTIONS

All the subjects underwent SVF and nocturnal polysomnography. Sleep videofluoroscopy was performed before and after sleep induction by intravenous injection of low-dose midazolam (2 mg per person) and was recorded during 3 kinds of events: awake, normoxygenation sleep, and desaturation sleep events.

MAIN OUTCOME MEASURES

Changes in SP length and the angle between inspiratory and expiratory efforts in each group were evaluated according to sleep events; changes in the SP was assessed according to obstruction sites and severity of OSA.

RESULTS

Desaturation sleep events were detected in all patients with OSA but not in simple snorers. In awake events, inspiratory efforts increased the length and angle of the SP in patients with OSA but not in simple snorers. Elongation and angulation were greatest during desaturation sleep events and least during awake events. In normoxygenation events, changes in the SP were significantly larger in patients with OSA than in simple snorers (P < .01 for SP length; P = .03 for SP angle). Elongation of the SP was the biggest in SP-type obstruction.

CONCLUSIONS

Sleep videofluoroscopy quantitatively showed that the SP was considerably elongated and angulated in patients with OSA even in an awake state. It is an easy way to measure the SP changes and may be a useful technique to differentiate OSA from simple snoring with short examination time.

摘要

目的

通过睡眠荧光透视检查(SVF)定量评估软腭(SP)的变化。

设计

回顾性分析。

地点

学术三级转诊中心。

患者

共63例连续的打鼾或睡眠呼吸暂停患者(53例阻塞性睡眠呼吸暂停[OSA]患者和10例单纯打鼾者)。

干预措施

所有受试者均接受SVF和夜间多导睡眠图检查。通过静脉注射低剂量咪达唑仑(每人2mg)诱导睡眠前后进行睡眠荧光透视检查,并在3种状态下记录:清醒、正常氧合睡眠和低氧睡眠状态。

主要观察指标

根据睡眠状态评估每组中SP长度的变化以及吸气和呼气动作之间的角度;根据OSA的阻塞部位和严重程度评估SP的变化。

结果

所有OSA患者均检测到低氧睡眠状态,但单纯打鼾者未检测到。在清醒状态下,吸气动作会增加OSA患者的SP长度和角度,但单纯打鼾者不会。在低氧睡眠状态下伸长和角度变化最大,清醒状态下最小。在正常氧合状态下,OSA患者的SP变化明显大于单纯打鼾者(SP长度P < 0.01;SP角度P = 0.03)。SP型阻塞时SP的伸长最大。

结论

睡眠荧光透视检查定量显示,即使在清醒状态下,OSA患者的SP也会显著伸长和形成角度。这是一种测量SP变化的简便方法,且检查时间短,可能是一种区分OSA和单纯打鼾的有用技术。

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