Department of Pharmaceutical Biology, Julius-von-Sachs-Institute, Biocenter, Julius-Maximilians-Universität Würzburg, Würzburg 97082, Germany.
Department of Pharmaceutical Biology, Julius-von-Sachs-Institute, Biocenter, Julius-Maximilians-Universität Würzburg, Würzburg 97082, Germany.
Trends Plant Sci. 2018 May;23(5):422-433. doi: 10.1016/j.tplants.2018.02.003. Epub 2018 Mar 7.
Sustaining energy homeostasis is crucial to every living being. To balance energy supply and demand, plants make use of an evolutionarily conserved management system consisting of two counteracting kinases, TOR (TARGET OF RAPAMYCIN) and SnRK1 (Snf1-RELATED PROTEIN KINASE 1). SnRK1 is involved in reorganizing enzymatic and transcriptional responses to survive energy-limiting conditions. Recently, members of the bZIP (basic leucine zipper) transcription factor family have been established as SnRK1 downstream mediators. We review here current knowledge on the functional impact of these group C and S bZIPs, and analyze their regulation by environmental and endogenous cues. Given their specific homo- and heterodimerization, the so-called C/S bZIP network is proposed to act as a signaling hub that coordinates plant development and stress responses.
维持能量平衡对每个生物都是至关重要的。为了平衡能量的供给和需求，植物利用了一种进化上保守的管理系统，该系统由两种相互拮抗的激酶组成，即 TOR（雷帕霉素的靶点）和 SnRK1（Snf1-RELATED PROTEIN KINASE 1）。SnRK1 参与重新组织酶和转录反应以在能量有限的条件下生存。最近，bZIP（碱性亮氨酸拉链）转录因子家族的成员已被确定为 SnRK1 的下游介质。在这里，我们回顾了这些组 C 和 S bZIP 的功能影响的最新知识，并分析了它们对环境和内源性信号的调节。由于它们的特定同源和异源二聚化，所谓的 C/S bZIP 网络被提议作为一个信号枢纽，协调植物发育和应激反应。
