Department of Pharmaceutical Outcomes and Policy, University of Florida, United States.
Center for Population Research, National Institute of Public Health, 7a. Cerrada de Fray Pedro de Gante #50, Col. Sección XVI Tlalpan, C.P. 14080 México D.F., Mexico.
J Affect Disord. 2018 Jul;234:109-116. doi: 10.1016/j.jad.2018.02.036. Epub 2018 Feb 28.
Depression is among the 10 major causes of disability in Mexico. Yet, local contextual factors associated to the disorder remain poorly understood. We measured the impact of several factors on severe depression such as demographics, pharmacotherapy, multimorbidity, and unhealthy behaviors in Mexican teachers.
A total of 43,845 Mexican female teachers from 12 Mexican states answered the Patient Health Questionnaire (PHQ9). Data were part the Mexican Teacher's Cohort prospective study, the largest ongoing cohort study in Latin America. Unadjusted and adjusted estimates assessed the impact of several contextual factors between severe versus mild-no depression cases.
In total 7026 teachers (16%) had a PHQ9 score compatible with severe depression. From them, only 17% received psychotropics, compared to 60% for those with a formal diagnosis. Less than 5% of teachers with PHQ9 scores compatible with severe depression had a formal diagnosis. Adjusted analysis reported higher odds of pharmacotherapy, having ≥ 3 comorbidities, higher levels of couple, family and work stress, fewer hours of vigorous physical activity, higher alcohol consumption, and smoking as risk factors for severe depression. Also, rural residents of northern and center states appeared more severely depressed compared to their urban counterparts. On average, the PHQ9 scores differed by ~ 10 points between severe and mild-no depressed teachers.
A cross-sectional design. Also, the study focused on female teachers between ages 25 and 74 years old, reducing the generalizability of the estimates.
Under-diagnosis of clinical depression in Mexican teachers is concerning. Unhealthy behavior is associated with severe depression. The information collected in this study represents an opportunity to build prevention mechanisms of depression in high-risk subgroups of female educators and warrants improving access to mental care in Mexico.
抑郁症是墨西哥 10 大残疾原因之一。然而,与该疾病相关的当地情境因素仍知之甚少。我们测量了几个因素对墨西哥教师严重抑郁症的影响,如人口统计学、药物治疗、多病共存和不健康行为。
来自墨西哥 12 个州的 43845 名墨西哥女教师回答了患者健康问卷 (PHQ9)。数据是墨西哥教师队列前瞻性研究的一部分,这是拉丁美洲正在进行的最大队列研究。未调整和调整后的估计评估了严重与轻度-无抑郁病例之间的几个情境因素的影响。
共有 7026 名教师(16%)PHQ9 评分符合严重抑郁症。其中,只有 17%接受了精神药物治疗,而有正式诊断的教师则为 60%。不到 5%的 PHQ9 评分符合严重抑郁症的教师有正式诊断。调整分析报告称,药物治疗、有≥3 种合并症、更高程度的夫妻、家庭和工作压力、更少的剧烈体育活动时间、更高的酒精摄入量和吸烟作为严重抑郁症的风险因素的可能性更高。此外,北部和中部各州的农村居民比城市居民看起来更严重抑郁。平均而言,严重和轻度-无抑郁教师的 PHQ9 评分相差约 10 分。
横断面设计。此外,该研究集中在 25 至 74 岁的女性教师,降低了估计的普遍性。
对墨西哥教师临床抑郁症的诊断不足令人担忧。不健康的行为与严重抑郁症有关。本研究收集的信息为在女性教育工作者的高危亚组中建立抑郁症预防机制提供了机会,并需要改善墨西哥的精神保健服务。