Division of Diabetes, Metabolism and Endocrinology, Kawasaki Medical School, Okayama, Japan.
Iwamoto Medical Clinic, Kagawa, Japan.
J Diabetes Investig. 2019 Jan;10(1):104-107. doi: 10.1111/jdi.12832. Epub 2018 Mar 30.
We retrospectively evaluated the effects of mild physical exercise (P) in a routine clinical setting on glycemic and bodyweight control in Japanese type 2 diabetes patients with and without individualized nutritional therapy (D). We analyzed 49 patients who participated in P that measured 2.5 metabolic equivalents and was held once every 2 weeks, compared with 83 non-participant controls, followed over a period of approximately 1.6 years. With a Cox model, the adjusted hazard ratio for improved glycated hemoglobin by numerical count of P was 1.03 (95% confidence interval [CI] 1.00-1.07; P = 0.025). Among four categories - with neither P nor D, only P, only D, and both P and D - the hazard ratios for reduced body mass index were 1.0, 0.87 (95% CI 0.46-1.67), 0.58 (95% CI 0.25-1.30) and 2.17 (95% CI 1.03-4.59), respectively. Even mild physical exercise contributed to glycemic control. The combination of P and D exerted beneficial effects on bodyweight control.
我们回顾性评估了在常规临床环境中进行轻度体育锻炼（P）对有和没有个体化营养治疗（D）的日本 2 型糖尿病患者血糖和体重控制的影响。我们分析了 49 名参加过 2.5 代谢当量的 P 的患者，这些患者每两周进行一次 P，与 83 名非参与者对照，随访时间约为 1.6 年。使用 Cox 模型，P 的数值计数对糖化血红蛋白改善的调整后危害比为 1.03（95%置信区间 [CI] 1.00-1.07；P = 0.025）。在四个类别 - 既没有 P 也没有 D、只有 P、只有 D 和 P 和 D 都有 - 体重指数降低的危害比分别为 1.0、0.87（95%CI 0.46-1.67）、0.58（95%CI 0.25-1.30）和 2.17（95%CI 1.03-4.59）。即使是轻度的体育锻炼也有助于血糖控制。P 和 D 的结合对体重控制有有益的影响。
