Bolze P-A, Paparel P, Golfier F
Université Claude-Bernard Lyon 1, hôpitaux universitaires de Lyon, centre hospitalier Lyon-Sud, service de chirurgie gynécologique et oncologique - obstétrique, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite, France.
Université Claude-Bernard Lyon 1, hôpitaux universitaires de Lyon, centre hospitalier Lyon-Sud, service de chirurgie urologique, 165, chemin du Grand Revoyet, 69495 Pierre-Bénite.
Gynecol Obstet Fertil Senol. 2018 Mar;46(3):301-308. doi: 10.1016/j.gofs.2018.02.016. Epub 2018 Mar 9.
Urinary tract involvement by endometriosis is reported in 1% of endometriosis patients (NP3). Consequences range from pelvic pain for bladder localizations to silent kidney loss in case of chronic ureteral obstruction (NP3). The feasibility of laparoscopic management was widely proven (NP3) and may reduce hospital stay length (NP4). Radical surgery with partial cystectomy for bladder localizations was shown to significantly and durably reduce pain symptoms with low risk of a severe postoperative complications (NP3). Medical hormonal treatment also shows short-term reduction of pain symptoms (NP4). Transureteral resection of bladder endometriosis nodule is not recommended (grade C) because of a high postoperative recurrence rate (NP4). Given a high risk of silent kidney loss, it is recommended that patients with ureteral involvement by endometriosis are managed by a multidisciplinary team considering urinary and potential extra-urinary localizations of endometriosis (grade C). No recommendation can be made on which technique to prefer between conservative (ureterolysis) or radical surgical techniques or on benefit and length of ureteral stents in case of ureteral involvement. Surgical management of bladder and ureteral localizations of endometriosis do not seem to be associated with altered or improved postoperative fertility (NP4). Since late postoperative ureteral anastomosis stenosis were reported with silent kidney loss, repeated postoperative imaging monitoring is justified (expert opinion).
1%的子宫内膜异位症患者有泌尿道受累情况(NP3)。其后果从膀胱部位的盆腔疼痛到慢性输尿管梗阻导致的隐匿性肾丧失不等(NP3)。腹腔镜治疗的可行性已得到广泛证实(NP3),且可能缩短住院时间(NP4)。对于膀胱部位的病灶,行部分膀胱切除术的根治性手术可显著且持久地减轻疼痛症状,术后严重并发症风险低(NP3)。药物激素治疗也显示出可短期减轻疼痛症状(NP4)。不推荐经输尿管切除膀胱子宫内膜异位结节(C级),因为术后复发率高(NP4)。鉴于隐匿性肾丧失风险高,建议由多学科团队管理输尿管受累的子宫内膜异位症患者,同时考虑子宫内膜异位症的泌尿道及潜在的非泌尿道病灶(C级)。对于保守手术(输尿管松解术)或根治性手术技术之间更倾向于哪种技术,以及输尿管受累时输尿管支架的益处和留置时间,无法给出推荐。子宫内膜异位症膀胱和输尿管病灶的手术治疗似乎与术后生育能力的改变或改善无关(NP4)。由于有术后晚期输尿管吻合口狭窄伴隐匿性肾丧失的报道,术后反复进行影像学监测是合理的(专家意见)。