Khayyer Zahra, Ngaosuvan Leonard, Sikström Sverker, Ghaderi Amir Hossein
Educational Sciences & Psychology Department, University of Isfahan, Isfahan, Iran. E-mail:
Department of Health and Work Science, University of Gävle, Gävle, Sweden. E-mail:
J Integr Neurosci. 2018;17(2):89-96. doi: 10.31083/JIN-170045.
Frontal cortex activity is reduced in the left hemisphere during depression. Transcranial direct current stimulation is a noninvasive neuromodulation technique that can increase frontal cortex activity. Therapy based on transcranial Direct Current Stimulation and positive psychology therapy was applied for improving patients’ quality of life. The present study compared three conditions of subjects with clinical depression; (a) transcranial Direct Current Stimulation therapy, (b) positive psychotherapy, and(c) combined treatment. Hamilton Depression Rating Scale, Adult State Hope Scale and Optimism/Pessimism Scale was used at baseline, 2-week, 4-week, and 3-month follow-up. Combined condition participants showed greater reduction in depressed mood, improved hope and optimism after 4-weeks as well as during 3-month follow-up than the other conditions. Results are discussed in terms of additive or synergistic relation between transcranial direct current stimulation and positive psychology treatment.
抑郁症患者左侧半球的额叶皮质活动会减少。经颅直流电刺激是一种非侵入性神经调节技术，可增加额叶皮质活动。基于经颅直流电刺激和积极心理治疗的疗法被应用于改善患者的生活质量。本研究比较了临床抑郁症患者的三种情况：(a)经颅直流电刺激疗法，(b)积极心理治疗，以及(c)联合治疗。在基线、2周、4周和3个月随访时使用汉密尔顿抑郁量表、成人状态希望量表和乐观/悲观量表。联合治疗组的参与者在4周后以及3个月随访期间，与其他情况相比，抑郁情绪有更大程度的减轻，希望和乐观情绪有所改善。研究结果从经颅直流电刺激与积极心理治疗之间的相加或协同关系方面进行了讨论。
