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本文引用的文献

1
A multicenter, open-label, pilot study evaluating the functionality of an integrated call center for a digital medicine system to optimize monitoring of adherence to oral aripiprazole in adult patients with serious mental illness.一项多中心、开放标签的试点研究,评估数字医学系统综合呼叫中心的功能,以优化对患有严重精神疾病的成年患者口服阿立哌唑依从性的监测。
Neuropsychiatr Dis Treat. 2017 Oct 19;13:2641-2651. doi: 10.2147/NDT.S143091. eCollection 2017.
2
Effectiveness of Digital Medicines to Improve Clinical Outcomes in Patients with Uncontrolled Hypertension and Type 2 Diabetes: Prospective, Open-Label, Cluster-Randomized Pilot Clinical Trial.数字药物改善血压控制不佳的高血压患者和2型糖尿病患者临床结局的有效性:前瞻性、开放标签、整群随机试验性临床试验
J Med Internet Res. 2017 Jul 11;19(7):e246. doi: 10.2196/jmir.7833.
3
Usability of a novel digital medicine system in adults with schizophrenia treated with sensor-embedded tablets of aripiprazole.一种新型数字药物系统在使用含阿立哌唑传感器片剂治疗的成年精神分裂症患者中的可用性。
Neuropsychiatr Dis Treat. 2016 Oct 11;12:2587-2594. doi: 10.2147/NDT.S116029. eCollection 2016.
4
Interventions for enhancing medication adherence.提高药物依从性的干预措施。
Cochrane Database Syst Rev. 2014 Nov 20;2014(11):CD000011. doi: 10.1002/14651858.CD000011.pub4.
5
A qualitative study of the attitudes of patients in an early intervention service towards antipsychotic long-acting injections.一项关于早期干预服务中患者对抗精神病长效注射态度的定性研究。
Ther Adv Psychopharmacol. 2014 Oct;4(5):179-85. doi: 10.1177/2045125314542098.
6
Patients' and clinicians' attitude towards long-acting depot antipsychotics in subjects with a first episode of psychosis.首发精神病患者长效 depot 抗精神病药治疗的患者和临床医生的态度。
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First experience with a wireless system incorporating physiologic assessments and direct confirmation of digital tablet ingestions in ambulatory patients with schizophrenia or bipolar disorder.在伴有精神分裂症或双相情感障碍的门诊患者中,采用整合生理评估和直接确认数字药片摄入的无线系统的首次应用经验。
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A prospective 3-year longitudinal study of cognitive predictors of relapse in first-episode schizophrenic patients.一项针对首发精神分裂症患者复发认知预测因素的前瞻性3年纵向研究。
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Overview of partial compliance.部分合规概述。
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数字医疗系统能否提高抗精神病药物治疗的依从性?

Can a digital medicine system improve adherence to antipsychotic treatment?

机构信息

Department of Neuroscience,Biomedicine and Movement Sciences, Section of Psychiatry, University of Verona,Verona,Italy.

出版信息

Epidemiol Psychiatr Sci. 2018 Jun;27(3):227-229. doi: 10.1017/S2045796018000082. Epub 2018 Mar 12.

DOI:10.1017/S2045796018000082
PMID:29528032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6998860/
Abstract

A substantial proportion of people with mental health conditions do not adhere to prescribed pharmacological treatments. Poor adherence is probably one of the most critical elements contributing to relapse in people with schizophrenia and other severe mental disorders. In order to tackle this global issue, in November 2017 the Food and Drug Administration approved a tablet formulation of the atypical antipsychotic aripiprazole embedded with a novel digital adherence-assessment device. In this commentary, we critically appraised the potential beneficial and harmful consequences of this new digital formulation of aripiprazole, and we highlighted expected implications for clinical practice.

摘要

相当一部分患有精神健康问题的人不遵守规定的药物治疗方案。治疗依从性差可能是导致精神分裂症和其他严重精神障碍患者病情复发的最重要因素之一。为了解决这个全球性问题,食品和药物管理局于 2017 年 11 月批准了一种将新型数字药物依从性评估装置嵌入其中的非典型抗精神病药阿立哌唑的片剂制剂。在这篇评论中,我们批判性地评估了这种新型阿立哌唑数字配方的潜在有益和有害后果,并强调了对临床实践的预期影响。