Intrinsik Corporation, Ottawa, Ontario, Canada.
Colgate-Palmolive Company, New York, New York, USA.
Integr Environ Assess Manag. 2018 Jul;14(4):437-441. doi: 10.1002/ieam.4042. Epub 2018 Apr 24.
Triclosan is an antibacterial and antifungal chemical used in a variety of consumer products, including soaps, detergents, moisturizers, and cosmetics. Aquatic ecosystems may be exposed to triclosan following the release of remaining residues in wastewater effluents and biosolids. In December 2017, Environment and Climate Change Canada (ECCC) released a federal environmental quality guideline (FEQG) report that contained a federal water quality guideline (FWQG) for triclosan. This guideline will be used as an adjunct to the risk assessment and risk management of priority chemicals identified under the Government of Canada's Chemicals Management Plan (CMP). The FWQG value for triclosan (0.47 μg/L) was derived by ECCC using a hazardous concentration for 5% of species (HC5) from a species sensitivity distribution (SSD). We recalculated the FWQG after performing an independent analysis and evaluation of the available aquatic toxicity data for triclosan and compared our results with the ECCC FWQG value. Our independent analysis of the available aquatic toxicity data entailed conducting a literature search of all available and relevant studies, evaluating the quality and reliability of all studies considered using thorough and consistent study evaluation criteria, and thereby generating a data set of high-quality toxicity values. The selected data set includes 22 species spanning 5 taxonomic groups. An SSD was developed using this data set following the ECCC approaches. The HC5 from the SSD derived based on our validated data set is 0.76 μg/L. This HC5 value is slightly greater (i.e., less sensitive) than the value presented in ECCC's final FWQG. Integr Environ Assess Manag 2018;14:437-441. © 2018 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC).
三氯生是一种抗菌和抗真菌化学物质,用于各种消费品,包括肥皂、洗涤剂、保湿霜和化妆品。水生生态系统可能会在废水和生物固体中残留的残留物释放后接触到三氯生。2017 年 12 月,加拿大环境与气候变化部(ECCC)发布了一份联邦环境质量指南(FEQG)报告,其中包含三氯生的联邦水质指南(FWQG)。该指南将作为加拿大政府化学品管理计划(CMP)下确定的优先化学品风险评估和风险管理的辅助手段。ECCC 使用物种敏感度分布(SSD)中的 5%物种有害浓度(HC5)来推导三氯生的 FWQG 值(0.47μg/L)。在对三氯生的现有水生毒性数据进行独立分析和评估后,我们重新计算了 FWQG,并将我们的结果与 ECCC 的 FWQG 值进行了比较。我们对现有水生毒性数据的独立分析包括对所有可用和相关研究进行文献检索,使用彻底和一致的研究评估标准评估所有考虑的研究的质量和可靠性,从而生成高质量毒性值数据集。选定的数据集中包含 22 个物种,涵盖 5 个分类群。使用该数据集按照 ECCC 的方法开发了 SSD。基于我们验证后的数据,SSD 得出的 HC5 为 0.76μg/L。这个 HC5 值比 ECCC 最终 FWQG 中提出的值略高(即更不敏感)。综合环境评估与管理 2018;14:437-441。©2018 作者。综合环境评估与管理由 Wiley 期刊出版公司代表环境毒理与化学学会(SETAC)出版。