左房容积、形态和纤维化对房颤导管消融治疗结局的影响。
Impact of left atrial volume, sphericity, and fibrosis on the outcome of catheter ablation for atrial fibrillation.
机构信息
Institut Clínic Cardiovascular, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.
Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
出版信息
J Cardiovasc Electrophysiol. 2018 May;29(5):740-746. doi: 10.1111/jce.13482. Epub 2018 Apr 6.
INTRODUCTION
To investigate the relation between left atrial (LA) volume, sphericity, and fibrotic content derived from contrast-enhanced cardiac magnetic resonance imaging (CE-CMR) and their impact on the outcome of catheter ablation for atrial fibrillation (AF).
METHODS AND RESULTS
In 83 patients undergoing catheter ablation for AF, CE-CMR was used to assess LA volume, sphericity, and fibrosis. There was a significant correlation between LA volume and sphericity (R = 0.535, P < 0.001) and between LA volume and fibrosis (R = 0.241, P = 0.029). Multivariate analyses demonstrated that LA volume was the strongest independent predictor of AF recurrence after catheter ablation (1.019, P = 0.018).
CONCLUSION
LA volume, sphericity, and fibrosis were closely related; however, LA volume was the strongest predictor of AF recurrence after catheter ablation.
简介
为了研究左心房（LA）容积、球形度和对比增强心脏磁共振成像（CE-CMR）得出的纤维化含量之间的关系，以及它们对房颤（AF）导管消融治疗结果的影响。
方法和结果
在 83 例接受 AF 导管消融治疗的患者中，使用 CE-CMR 评估 LA 容积、球形度和纤维化。LA 容积和球形度之间存在显著相关性（R = 0.535，P < 0.001），LA 容积和纤维化之间也存在显著相关性（R = 0.241，P = 0.029）。多变量分析表明，LA 容积是导管消融后 AF 复发的最强独立预测因子（1.019，P = 0.018）。
结论
LA 容积、球形度和纤维化密切相关；然而，LA 容积是导管消融后 AF 复发的最强预测因子。
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