Institut Clínic Cardiovascular, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.
Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
J Cardiovasc Electrophysiol. 2018 May;29(5):740-746. doi: 10.1111/jce.13482. Epub 2018 Apr 6.
To investigate the relation between left atrial (LA) volume, sphericity, and fibrotic content derived from contrast-enhanced cardiac magnetic resonance imaging (CE-CMR) and their impact on the outcome of catheter ablation for atrial fibrillation (AF).
In 83 patients undergoing catheter ablation for AF, CE-CMR was used to assess LA volume, sphericity, and fibrosis. There was a significant correlation between LA volume and sphericity (R = 0.535, P < 0.001) and between LA volume and fibrosis (R = 0.241, P = 0.029). Multivariate analyses demonstrated that LA volume was the strongest independent predictor of AF recurrence after catheter ablation (1.019, P = 0.018).
LA volume, sphericity, and fibrosis were closely related; however, LA volume was the strongest predictor of AF recurrence after catheter ablation.
为了研究左心房（LA）容积、球形度和对比增强心脏磁共振成像（CE-CMR）得出的纤维化含量之间的关系，以及它们对房颤（AF）导管消融治疗结果的影响。
在 83 例接受 AF 导管消融治疗的患者中，使用 CE-CMR 评估 LA 容积、球形度和纤维化。LA 容积和球形度之间存在显著相关性（R = 0.535，P < 0.001），LA 容积和纤维化之间也存在显著相关性（R = 0.241，P = 0.029）。多变量分析表明，LA 容积是导管消融后 AF 复发的最强独立预测因子（1.019，P = 0.018）。
LA 容积、球形度和纤维化密切相关；然而，LA 容积是导管消融后 AF 复发的最强预测因子。
