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[卫生人员中乙型肝炎的筛查与疫苗接种。短期结果]

[Screening and vaccination against hepatitis B among health personnel. Short-term results].

作者信息

Bertoglio C, Ariotti G, Demicheli V, Marino G, Piccinelli V, Leccardi E, Allosia G P, Corti E, Ballerini P

出版信息

Minerva Med. 1987 Apr 30;78(8):537-42.

PMID:2952903
Abstract

In the framework of the campaign for anti-HBV vaccination conducted by the Regione Piemonte, the Mauriziano Hospital in Valenza and the Unità Sanitaria Locale 71, screened and then vaccinated a group of 199 medical workers at risk of HBV. It was found that the infection was asymptomatic in the vaccinated subjects (16%) and the chronic HBsAg carriers (1.5%), that the risk of infection increases with age (p less than 0.01) and length of service (p less than 0.05) and that there is a connection with the mean figures produced by other studies conducted on hospital staff. Vaccination gave satisfactory results, with protective antibody responses in 87% of the cases, of whom about half presented levels over 1000 mIU/ml and no significant side effects.

摘要

在皮埃蒙特地区开展的抗乙肝病毒疫苗接种活动框架内,瓦伦扎的毛里齐亚诺医院和当地卫生机构71对一组199名有乙肝病毒感染风险的医护人员进行了筛查,然后为他们接种了疫苗。结果发现,接种疫苗的受试者(16%)和慢性乙肝表面抗原携带者(1.5%)的感染无症状,感染风险随年龄(p<0.01)和服务年限(p<0.05)增加,且与其他针对医院工作人员的研究得出的平均数据有关联。疫苗接种取得了令人满意的结果,87%的病例产生了保护性抗体反应,其中约一半的抗体水平超过1000 mIU/ml,且无明显副作用。

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