Product Development Group Zurich, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland.
Product Development Group Zurich, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland.
Ann Thorac Surg. 2018 May;105(5):1558-1562. doi: 10.1016/j.athoracsur.2017.11.010. Epub 2018 Mar 9.
Less invasive left ventricular assist device implantation became feasible with the development of smaller devices. This study evaluated a sutureless aortic anastomosis device to facilitate the implant procedure.
The novel anastomotic device deploys and anchors an acute-angled stent in the aortic wall to create a sutureless outflow graft anastomosis in the ascending aorta. Four aortic anastomoses were performed on the beating hearts of two pigs without cross-clamping or cardiopulmonary bypass.
The procedure was fast and simple. The time of anastomosis averaged 8.1 minutes, with merely oral instructions to the operating surgeon. The design of the stent allowed the outflow graft to be implanted with the intended angulation of 45 degrees.
This proof-of-concept study demonstrates the feasibility and short-term success of the proposed sutureless anastomotic device. Further preclinical studies are necessary to evaluate long-term durability of the anastomosis.
随着更小设备的发展，微创左心室辅助装置的植入变得可行。本研究评估了一种无缝合主动脉吻合装置，以促进植入过程。
新型吻合装置在主动脉壁中部署并固定一个锐角支架，在升主动脉中创建一个无缝合的流出移植物吻合口。在没有交叉钳夹或体外循环的情况下，在两只猪的跳动心脏上进行了 4 次主动脉吻合。
该过程快速而简单。吻合的平均时间为 8.1 分钟，只需向手术医生口头说明即可。支架的设计允许以 45 度的预期角度植入流出移植物。
这项概念验证研究证明了所提出的无缝合吻合装置的可行性和短期成功。需要进一步的临床前研究来评估吻合的长期耐久性。
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