The National Institutes of Health Heart Center at Suburban Hospital, Bethesda, Maryland.
The National Institutes of Health Heart Center at Suburban Hospital, Bethesda, Maryland.
Ann Thorac Surg. 2018 Jun;105(6):1684-1690. doi: 10.1016/j.athoracsur.2018.02.008. Epub 2018 Mar 9.
Prolonged intubation after cardiac surgery is associated with significant morbidity. A fast-track extubation protocol primarily driven by bedside providers was instituted for all postoperative cardiac surgery patients to facilitate safe and expeditious extubation.
A retrospective review of 1,581 cardiac surgery patients over an 8-year period was performed. Before 2011, nonprotocolized standard perioperative management was utilized (n = 807). From 2011 onward, a fast-track extubation (FTE) protocol directed by bedside providers was instituted (n = 774). Postoperatively, patients were placed on pressure-regulated volume control and titrated down to minimal support to maintain peripheral capillary oxygen saturation greater than 94%. For patients deemed ready for weaning (no evidence of hypoxia, hemodynamic instability, and so forth), a 30-minute continuous positive airway pressure trial was performed. Patients meeting all neurologic, respiratory, and cardiovascular criteria were extubated. The impact of the FTE algorithm on timely extubation, clinical outcomes, and safety was assessed.
Baseline preoperative and intraoperative characteristics were similar between pre-FTE and FTE groups. Before instituting the FTE protocol, the rate of early extubation (less than 6 hours) was 43.7%, and increased to 64.1% during the FTE era (p < 0.001). Median time to extubation was also found to be significantly decreased: 295 minutes (interquartile range: 288) versus 385 minutes (interquartile range: 362, p = 0.041). There was no statistically significant difference in reintubation rates or 30-day mortality.
The institution of a bedside provider-directed FTE pathway reduced overall intubation times and increased the rate of early extubation, without an increase in reintubation or mortality. This program-wide multidisciplinary approach appears to promote safe and expeditious extubation of cardiac surgery patients.
心脏手术后长时间插管与显著的发病率有关。为了促进安全、快速拔管,我们为所有心脏手术后患者制定了一个主要由床边医护人员驱动的快速脱机方案。
对 8 年内的 1581 例心脏手术患者进行回顾性分析。2011 年之前,采用非方案标准化围手术期管理(n=807)。从 2011 年开始,实施了由床边医护人员指导的快速脱机(FTE)方案(n=774)。术后,患者采用压力调节容量控制模式,并逐渐减少支持以维持外周毛细血管血氧饱和度大于 94%。对于被认为可以脱机的患者(无缺氧、血流动力学不稳定等证据),进行 30 分钟持续气道正压通气试验。如果患者满足所有神经、呼吸和心血管标准,就可以拔管。评估 FTE 算法对及时拔管、临床结局和安全性的影响。
在 FTE 方案实施之前和实施之后,患者的术前和术中基线特征相似。在实施 FTE 方案之前,早期拔管(6 小时内)的比例为 43.7%,在 FTE 时代增加到 64.1%(p<0.001)。拔管时间中位数也明显缩短:295 分钟(四分位距:288)与 385 分钟(四分位距:362,p=0.041)。再插管率或 30 天死亡率没有统计学差异。
床边医护人员主导的 FTE 方案的实施降低了总插管时间,提高了早期拔管的比例,而不增加再插管或死亡率。这种全范围的多学科方法似乎促进了心脏手术患者的安全、快速拔管。