Laboratoire d'écobiologie animale, école normale supérieure de Kouba, Alger, Algeria; Département de biologie, faculté des sciences de la nature et de la vie, université Hassiba ben Bouali, CHLEF, Algeria; Institut des Neurosciences Paris-Saclay, Université Paris Sud 11, CNRS 9197, Orsay, France.
Laboratoire d'écobiologie animale, école normale supérieure de Kouba, Alger, Algeria.
J Chem Neuroanat. 2018 Nov;93:57-61. doi: 10.1016/j.jchemneu.2018.03.003. Epub 2018 Mar 9.
The objective of this work was to investigate the implication of serotonin (5-HT) produced in the dorsal and medial raphé nuclei (DRN and MRN) in water homeostasis in desert animal Gerbillus tarabuli. For that, we measured the density of 5-HT immunolabeled neurons in hydrated and dehydrated animals (over 1 and six months). In this work, 5-HT positive neurons showed some change in shape and colour intensity in dehydrated gerbils comparing with hydrated gerbils. Furthermore a differential increase of 5-HT neurons density was observed in DRN subregions and in MRN following 1 and 6 months of dehydration. This study suggested that neurons in DRN and MRN contain 5-HT in various amounts, thus allowing an adapted response to hydration status. These neurons could mediate one of the adaptation mechanisms of this animal to its desert biotope.
这项工作的目的是研究沙漠动物沙鼠背侧和中缝核（DRN 和 MRN）中产生的 5-羟色胺（5-HT）在水稳态中的意义。为此，我们测量了水合和脱水动物（超过 1 个月和 6 个月）中 5-HT 免疫标记神经元的密度。在这项工作中，与水合沙鼠相比，脱水沙鼠的 5-HT 阳性神经元在形状和颜色强度上表现出一些变化。此外，在脱水 1 个月和 6 个月后，DRN 亚区和 MRN 中 5-HT 神经元的密度呈现出不同程度的增加。这项研究表明，DRN 和 MRN 中的神经元含有不同数量的 5-HT，从而能够对水合状态做出适应性反应。这些神经元可能介导了这种动物对沙漠生境的适应机制之一。
