PET/MR在评估克罗恩病活动性炎症中的诊断性能
Diagnostic performance of PET/MR in the evaluation of active inflammation in Crohn disease.
作者信息
Catalano Onofrio Antonio, Wu Vincent, Mahmood Umar, Signore Alberto, Vangel Mark, Soricelli Andrea, Salvatore Marco, Gervais Debra, Rosen Bruce R
机构信息
Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School149 13th Street Charlestown #2301, Boston 02129, MA, USA.
Abdominal Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School55 Fruit St, Boston 02114, MA, USA.
出版信息
Am J Nucl Med Mol Imaging. 2018 Feb 5;8(1):62-69. eCollection 2018.
Abstract
This study investigates the performance of PET/MR versus each sub-modality alone in the assessment of active inflammation in patients with Crohn disease, when compared to surgery as standard of reference. Sensitivity for detecting active inflammation was 91.5% for PET, 80% for MR, and 88% for PET/MR. Specificity for active inflammation was 74% for PET, 87% for MR, and 93% for PET/MR. Diagnostic accuracy was 84% for PET, 83% for MR, and 91% for PET/MR. In conclusion, PET/MR is significantly more accurate than either sub-modality alone and more specific than PET alone in the detection of active inflammation in patients with Crohn disease.
摘要
本研究将正电子发射断层显像/磁共振成像（PET/MR）与单独的每种子模态在评估克罗恩病患者的活动性炎症时的性能进行了调查，并与作为参考标准的手术进行比较。PET检测活动性炎症的敏感性为91.5%，MR为80%，PET/MR为88%。PET对活动性炎症的特异性为74%，MR为87%，PET/MR为93%。PET的诊断准确性为84%，MR为83%，PET/MR为91%。总之，在检测克罗恩病患者的活动性炎症方面，PET/MR比单独的任何一种子模态都显著更准确，且比单独的PET更具特异性。
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