利用2-氰基苯并噻唑/1,2-氨基硫醇生物正交点击反应对肽进行区域选择性标记的早期掺入策略
Early-Stage Incorporation Strategy for Regioselective Labeling of Peptides using the 2-Cyanobenzothiazole/ 1,2-Aminothiol Bioorthogonal Click Reaction.
作者信息
Chen Kuo-Ting, Ieritano Christian, Seimbille Yann
机构信息
Life Sciences Division TRIUMF Vancouver British Columbia V6T 2A3 Canada.
出版信息
ChemistryOpen. 2018 Feb 12;7(3):214. doi: 10.1002/open.201800016. eCollection 2018 Mar.
Invited for this month's cover picture is the group of Dr. Yann Seimbille at the Life Sciences Division at TRIUMF (Canada). The cover picture shows how a simple and innovative methodology based on the bioorthogonal click reaction between 2-cyanobenzothiazole and 1,2-aminothiol has been elaborated to facilitate the labeling of peptide biovectors. Read the full text of their Communication at 10.1002/open.201700191.
本期封面图片的受邀者是加拿大 TRIUMF 生命科学部的扬·桑比尔博士团队。封面图片展示了一种基于 2-氰基苯并噻唑与 1,2-氨基硫醇之间的生物正交点击反应的简单而创新的方法是如何精心设计出来以促进肽生物载体标记的。请阅读他们发表在 10.1002/open.201700191 上的通讯全文。
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