March C M, Israel R
Am J Obstet Gynecol. 1987 Apr;156(4):834-42. doi: 10.1016/0002-9378(87)90339-5.
Between April 1982 and April 1986, 91 patients underwent hysteroscopy for treatment of septate uteri. In 88 patients simultaneous laparoscopy was performed and one patient had a simultaneous laparotomy. Ninety procedures were performed on an outpatient basis with the patients under general anesthesia. The septum was incised with flexible scissors. Sequential estrogen-gestagen therapy was used immediately after operation to reepithelialize the freshly dissected surfaces. Patients were permitted to conceive in the first month after operation. The indications for hysteroscopy were multiple but included recurrent abortion in 79 patients. Among those patients in this category the pretreatment reproductive wastage was 95%. Most losses were in the first trimester. Among those patients who conceived after therapy, the gestational outcome markedly improved. Eighty-seven percent of the pregnancies have resulted in a living infant or have progressed beyond 20 weeks of gestation. Because the gestational outcome equals or exceeds that achieved by transabdominal metroplasty and because of its lower morbidity and the option for vaginal delivery, hysteroscopic incision of the symptomatic septate uterus should replace transabdominal metroplasty.
1982年4月至1986年4月期间,91例患者接受了宫腔镜检查以治疗纵隔子宫。其中88例患者同时进行了腹腔镜检查,1例患者同时进行了剖腹手术。90例手术在门诊进行,患者在全身麻醉下接受治疗。使用软性剪刀切开纵隔。术后立即采用序贯雌激素-孕激素疗法使新切开的表面重新上皮化。患者在术后第一个月即可受孕。宫腔镜检查的适应证多种多样,但79例患者的适应证为反复流产。在这一类患者中,治疗前的生殖损失率为95%。大多数流产发生在孕早期。在接受治疗后受孕的患者中,妊娠结局明显改善。87%的妊娠分娩出活婴或妊娠进展超过20周。由于妊娠结局等同于或优于经腹子宫成形术,且发病率较低并有经阴道分娩的选择,有症状的纵隔子宫的宫腔镜切开术应取代经腹子宫成形术。