Mutanen Annika, Pierro Agostino, Zani Augusto
Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada.
Eur J Pediatr Surg. 2018 Apr;28(2):148-151. doi: 10.1055/s-0038-1636943. Epub 2018 Mar 13.
Necrotizing enterocolitis (NEC) is a devastating condition that mainly affects premature infants. Advanced cases of NEC require surgical treatment, which in up to 70% of infants is associated with significant perioperative morbidity including anastomosis- or enterostomy-related complications, sepsis, peritonitis, and wound infections. Moreover, the perioperative complications may compromise the long-term gastrointestinal and neurodevelopmental outcome of patients requiring surgery for NEC.
坏死性小肠结肠炎(NEC)是一种主要影响早产儿的严重疾病。NEC的晚期病例需要手术治疗,在高达70%的婴儿中,手术会伴有显著的围手术期发病率,包括吻合口或肠造口相关并发症、败血症、腹膜炎和伤口感染。此外,围手术期并发症可能会影响因NEC而需要手术的患者的长期胃肠道和神经发育结局。