The Department of Surgical Sciences, The University of Rome "La Sapienza", Rome, Italy.
The Department of Surgical Sciences, The University of Rome "La Sapienza", Rome, Italy.
Int J Surg. 2018 Apr;52:329-333. doi: 10.1016/j.ijsu.2018.02.062. Epub 2018 Mar 10.
Tandem stenoses of the internal carotid artery (ICA) and proximal, ipsilateral common carotid artery (CCA) or innominate artery can be treated with a hybrid approach, combining conventional carotid endarterectomy (CEA) and retrograde stenting of the proximal stenosis, through surgical exposure of the carotid bifurcation. The purpose of this study was to evaluate the results of combining eversion CEA with retrograde CCA/innominate artery stenting.
From January 2015 to July 2017, 7 patients, 6 men of a mean age of 72 years (range 59-83 years) underwent simultaneous, retrograde stenting of the proximal CCA/innominate artery and an eversion CEA of the ipsilateral ICA, through surgical exposure of the carotid bifurcation, for severe tandem stenoses. The proximal stenosis involved the left proximal CCA in 4 patients, the proximal innominate artery in 2 patients and the right CCA in one patient. The procedure was performed under general anesthesia in a conventional operating room equipped with a mobile C-arm. A covered, balloon expandable stent was deployed over the proximal stenosis via a 6-F sheath directly introduced into the proximal CCA through the obliquely transected carotid bulb. After removing the sheath, debris were flushed through the carotid bulb and eversion CEA completed the procedure. Study endpoints were: postoperative stroke/mortality rate, cardiac mortality and morbidity, peripheral nerve injury, cervical hematoma, overall late survival, freedom from ipsilateral stroke and patency of arterial reconstruction.
No postoperative mortality or neurologic morbidity was observed in any patient. Cervical hematomas and peripheral nerve injuries were likewise absent. At a mean follow-up of 18 months, all the patients were alive, free from neurologic events of new onset and free from restenosis.
Combined proximal stenting and eversion CEA for tandem lesions seems a valid treatment, with the advantages of eversion CEA over other techniques of carotid bifurcation revascularization.
颈内动脉(ICA)和同侧颈总动脉(CCA)或无名动脉近端串联狭窄可以通过杂交手术治疗,即通过颈动脉分叉部的手术暴露,结合传统颈动脉内膜切除术(CEA)和近端狭窄的逆行支架置入。本研究的目的是评估外翻 CEA 联合逆行 CCA/无名动脉支架置入术的效果。
2015 年 1 月至 2017 年 7 月,7 例患者,6 例男性,平均年龄 72 岁(59-83 岁),因严重串联狭窄,在颈动脉分叉部手术暴露下,同期行同侧 ICA 外翻 CEA 和逆行CCA/无名动脉近端支架置入术。近端狭窄涉及 4 例左侧颈总动脉近端、2 例无名动脉近端和 1 例右侧颈总动脉。该手术在配备移动 C 臂的常规手术室全身麻醉下进行。通过直接从斜切颈动脉窦引入近端 CCA 的 6-F 鞘,在近端狭窄处以覆盖、球囊扩张支架进行逆行支架置入。移除鞘后,通过颈动脉窦冲洗碎片,外翻 CEA 完成手术。研究终点为:术后卒中/死亡率、心脏死亡率和发病率、周围神经损伤、颈部血肿、总晚期存活率、同侧卒中无复发率和动脉重建通畅率。
无术后死亡或神经功能障碍。亦无颈部血肿和周围神经损伤。平均随访 18 个月,所有患者均存活,无新发神经事件,无再狭窄。
串联病变的近端支架置入和外翻 CEA 联合治疗似乎是一种有效的治疗方法,外翻 CEA 比其他颈动脉分叉再血管化技术具有优势。