Characterization studies of human tissue-type plasminogen activator produced by recombinant DNA technology.

作者信息

Vehar G A, Spellman M W, Keyt B A, Ferguson C K, Keck R G, Chloupek R C, Harris R, Bennett W F, Builder S E, Hancock W S

出版信息

Cold Spring Harb Symp Quant Biol. 1986;51 Pt 1:551-62. doi: 10.1101/sqb.1986.051.01.067.

DOI:10.1101/sqb.1986.051.01.067

PMID:2953546

Abstract

摘要

相似文献

Characterization studies of human tissue-type plasminogen activator produced by recombinant DNA technology.

Cold Spring Harb Symp Quant Biol. 1986;51 Pt 1:551-62. doi: 10.1101/sqb.1986.051.01.067.

Quality control of rDNA-derived human tissue-type plasminogen activator.

Bioprocess Technol. 1990;10:543-66.

Novel recombinant tissue plasminogen activators produced in Escherichia coli.在大肠杆菌中产生的新型重组组织型纤溶酶原激活剂。

Ann N Y Acad Sci. 1990;613:452-4. doi: 10.1111/j.1749-6632.1990.tb18199.x.

Cloning of cDNA coding for human tissue-type plasminogen activator and its expression in Escherichia coli.编码人组织型纤溶酶原激活剂的cDNA克隆及其在大肠杆菌中的表达。

Mol Biol Med. 1986 Jun;3(3):279-92.

Tissue plasminogen activator has an O-linked fucose attached to threonine-61 in the epidermal growth factor domain.组织型纤溶酶原激活剂在表皮生长因子结构域的苏氨酸-61上连接有一个O-连接的岩藻糖。

Biochemistry. 1991 Mar 5;30(9):2311-4. doi: 10.1021/bi00223a004.

Purification and characterization of tissue plasminogen activator kringle-2 domain expressed in Escherichia coli.

Biochemistry. 1989 Feb 21;28(4):1884-91. doi: 10.1021/bi00430a068.

rtPA is a well-characterized protein.

Dev Biol Stand. 1998;96:113-21.

Synthesis and secretion of a fibrinolytically active tissue-type plasminogen activator variant in Escherichia coli.在大肠杆菌中合成并分泌具有纤维蛋白溶解活性的组织型纤溶酶原激活剂变体

Gene. 1991 Mar 15;99(2):243-8. doi: 10.1016/0378-1119(91)90133-v.

Expression, purification, and characterization of the recombinant kringle 1 domain from tissue-type plasminogen activator.

Arch Biochem Biophys. 1992 Apr;294(1):282-90. doi: 10.1016/0003-9861(92)90170-2.

Human tissue-type plasminogen activator synthesized by using a baculovirus vector in insect cells compared with human plasminogen activator produced in mouse cells.利用杆状病毒载体在昆虫细胞中合成的人组织型纤溶酶原激活剂与在小鼠细胞中产生的人纤溶酶原激活剂的比较。

Gene. 1988 Dec 20;73(2):449-57. doi: 10.1016/0378-1119(88)90509-4.

引用本文的文献

Feasibility study on spray-drying protein pharmaceuticals: recombinant human growth hormone and tissue-type plasminogen activator.蛋白质药物喷雾干燥的可行性研究：重组人生长激素和组织型纤溶酶原激活剂

Pharm Res. 1994 Jan;11(1):12-20. doi: 10.1023/a:1018929224005.

Surface denaturation at solid-void interface--a possible pathway by which opalescent particulates form during the storage of lyophilized tissue-type plasminogen activator at high temperatures.固-空界面处的表面变性——冻干组织型纤溶酶原激活剂在高温储存期间形成乳白色微粒的一种可能途径。

Pharm Res. 1995 Jan;12(1):69-77. doi: 10.1023/a:1016270103863.

Tissue-type plasminogen activator. A review of its pharmacology and therapeutic use as a thrombolytic agent.组织型纤溶酶原激活剂。其药理学及作为溶栓剂的治疗用途综述。

Drugs. 1989 Sep;38(3):346-88. doi: 10.2165/00003495-198938030-00003.

Different receptors mediate the hepatic catabolism of tissue-type plasminogen activator and urokinase.不同的受体介导组织型纤溶酶原激活剂和尿激酶的肝脏分解代谢。

Biochem J. 1990 May 1;267(3):647-52. doi: 10.1042/bj2670647.

Interspecies scaling of clearance and volume of distribution data for five therapeutic proteins.五种治疗性蛋白质清除率和分布容积数据的种间缩放

Pharm Res. 1991 Nov;8(11):1351-9. doi: 10.1023/a:1015836720294.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验