Mao Xiao-Chun, Chen Chao, Wang Ke-Jing
Department of Head and Neck Surgery, Zhejiang Cancer Hospital, Hangzhou, 310022, China.
Eur Arch Otorhinolaryngol. 2018 May;275(5):1257-1263. doi: 10.1007/s00405-018-4912-9. Epub 2018 Mar 13.
To compare the efficacy and safety profiles of LigaSure™ small jaw instrument (LSJI) versus conventional technique in patients undergoing open thyroidectomy.
This single-center, prospective, observational study conducted in Zhejiang Provincial Cancer Hospital enrolled patients who underwent thyroidectomy between September 2013 and September 2014. The primary study outcomes included determination of blood loss, operative duration, length of hospital stay, and drainage volume. The secondary outcomes included evaluation of recurrent laryngeal nerve palsy, postoperative bleeding, and hypoparathyroidism.
A total of 842 patients undergoing thyroidectomy either with conventional method (n = 440) or with LSJI (n = 402) were enrolled. A significantly reduced operative time and intraoperative blood loss were noted in the LSJI group (p < .001) compared with the conventional group. Further, the LSJI group also demonstrated a significantly lower postoperative drainage (p < .05) compared with the conventional group. Length of hospital stay and incidence of postoperative complications were similar in both the LSJI and conventional groups.
LigaSure hemostasis in thyroidectomy appears to result in significantly reduced operative time, intraoperative blood loss, and postoperative drainage compared with the conventional method in Chinese patients.
比较LigaSure™小颌器械（LSJI）与传统技术在接受开放性甲状腺切除术患者中的疗效和安全性。
这项在浙江省肿瘤医院进行的单中心、前瞻性观察性研究纳入了2013年9月至2014年9月期间接受甲状腺切除术的患者。主要研究结果包括确定失血量、手术时间、住院时间和引流量。次要结果包括评估喉返神经麻痹、术后出血和甲状旁腺功能减退。
共有842例接受甲状腺切除术的患者入组，其中440例采用传统方法，402例采用LSJI。与传统组相比，LSJI组的手术时间和术中失血量显著减少（p < .001）。此外，与传统组相比，LSJI组的术后引流量也显著更低（p < .05）。LSJI组和传统组的住院时间和术后并发症发生率相似。
在中国患者中，与传统方法相比，LigaSure在甲状腺切除术中止血似乎可显著减少手术时间、术中失血量和术后引流量。
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