Cruciani M, Concia E, Monzillo V, Marone P, Perversi L
Microbiologica. 1987 Apr;10(2):197-207.
The in vitro activity of antibiotic combination of teicoplanin and gentamicin (or netilmicin) and teicoplanin and cephalotin on Staphylococcus aureus was evaluated using the checkerboard method and time-kill curves. With few exceptions neither antagonism nor synergism was seen for the combination of teicoplanin and aminoglycosides using the checkerboard method. Using time-kill curves synergism was often found for the combination of teicoplanin and netilmicin (even at sub-minimal inhibitory concentrations of netilmicin) and for the combination of teicoplanin and cephalotin. No antagonistic interactions occurred.
采用棋盘法和时间-杀菌曲线评估了替考拉宁与庆大霉素（或奈替米星）以及替考拉宁与头孢噻吩联合应用对金黄色葡萄球菌的体外抗菌活性。除少数例外情况外，使用棋盘法时，替考拉宁与氨基糖苷类药物联合应用未见拮抗作用或协同作用。使用时间-杀菌曲线时，常发现替考拉宁与奈替米星联合应用（即使在奈替米星的亚最低抑菌浓度时）以及替考拉宁与头孢噻吩联合应用具有协同作用。未发生拮抗相互作用。
