• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The value of including thalamic atrophy as a clinical trial endpoint in multiple sclerosis.

作者信息

Schoonheim Menno M, Ciccarelli Olga

机构信息

From the Department of Anatomy and Neurosciences (M.M.S.), Amsterdam Neuroscience, MS Center Amsterdam, VU University Medical Center, the Netherlands; Department of Neuroinflammation (O.C.), UCL Institute of Neurology, University College London; and National Institute for Health Research (O.C.), University College London Hospitals Biomedical Research Centre, UK.

出版信息

Neurology. 2018 Apr 10;90(15):677-678. doi: 10.1212/WNL.0000000000005279. Epub 2018 Mar 14.

DOI:10.1212/WNL.0000000000005279
PMID:29540583
Abstract
摘要

相似文献

1
The value of including thalamic atrophy as a clinical trial endpoint in multiple sclerosis.将丘脑萎缩作为多发性硬化症临床试验终点的价值。
Neurology. 2018 Apr 10;90(15):677-678. doi: 10.1212/WNL.0000000000005279. Epub 2018 Mar 14.
2
Assessing the cerebral gray matter volume in response to fingolimod therapy in multiple sclerosis: A more analytic view.
J Neurol Sci. 2017 Dec 15;383:230-231. doi: 10.1016/j.jns.2017.10.018. Epub 2017 Oct 13.
3
A two-year study using cerebral gray matter volume to assess the response to fingolimod therapy in multiple sclerosis.一项为期两年的研究使用大脑灰质体积来评估多发性硬化症中 fingolimod 治疗的反应。
J Neurol Sci. 2017 Dec 15;383:221-229. doi: 10.1016/j.jns.2017.10.019. Epub 2017 Oct 16.
4
Deep gray matter atrophy in neuromyelitis optica spectrum disorder and multiple sclerosis.视神经脊髓炎谱系障碍和多发性硬化中的深部灰质萎缩
Eur J Neurol. 2017 Feb;24(2):437-445. doi: 10.1111/ene.13224. Epub 2016 Dec 23.
5
Thalamic lesions in multiple sclerosis by 7T MRI: Clinical implications and relationship to cortical pathology.7T磁共振成像显示的多发性硬化症丘脑病变：临床意义及其与皮质病理的关系
Mult Scler. 2015 Aug;21(9):1139-50. doi: 10.1177/1352458514558134. Epub 2015 Jan 12.
6
Predicting cognitive decline in multiple sclerosis: a 5-year follow-up study.多发性硬化症认知能力下降的预测：一项 5 年随访研究。
Brain. 2018 Sep 1;141(9):2605-2618. doi: 10.1093/brain/awy202.
7
Modeling the relationship among gray matter atrophy, abnormalities in connecting white matter, and cognitive performance in early multiple sclerosis.模拟早期多发性硬化症中灰质萎缩、连接性白质异常与认知表现之间的关系。
AJNR Am J Neuroradiol. 2015 Apr;36(4):702-9. doi: 10.3174/ajnr.A4165. Epub 2014 Nov 20.
8
The Development of Subcortical Gray Matter Atrophy in Multiple Sclerosis: One Size Does Not Fit All.多发性硬化症皮质下灰质萎缩的发展：一刀切并不适用于所有人。
AJNR Am J Neuroradiol. 2020 Sep;41(9):E80-E81. doi: 10.3174/ajnr.A6698. Epub 2020 Jul 9.
9
Retinal nerve fiber layer thickness and thalamus pathology in multiple sclerosis patients.多发性硬化症患者的视网膜神经纤维层厚度与丘脑病理学
Eur J Neurol. 2014 Aug;21(8):1137-e61. doi: 10.1111/ene.12449. Epub 2014 Apr 30.
10
Cortical atrophy patterns in multiple sclerosis are non-random and clinically relevant.多发性硬化症中的皮质萎缩模式具有非随机性且与临床相关。
Brain. 2016 Jan;139(Pt 1):115-26. doi: 10.1093/brain/awv337. Epub 2015 Dec 4.

引用本文的文献

1
Thalamic atrophy in multiple sclerosis is associated with tract disconnection and altered microglia.多发性硬化症中的丘脑萎缩与神经束断开和小胶质细胞改变有关。
Acta Neuropathol. 2025 May 28;149(1):52. doi: 10.1007/s00401-025-02893-4.
2
Quantification of Thalamic Atrophy in MS: From the Multicenter Italian Neuroimaging Network Initiative Data Set to Clinical Application.多发性硬化症患者丘脑萎缩的定量分析：来自多中心意大利神经影像学网络倡议数据集到临床应用。
AJNR Am J Neuroradiol. 2023 Dec 11;44(12):1399-1404. doi: 10.3174/ajnr.A8050.
3
Effect of ibudilast on thalamic magnetization transfer ratio and volume in progressive multiple sclerosis.
伊布地特对进展性多发性硬化症丘脑磁化传递率和体积的影响。
Mult Scler. 2023 Sep;29(10):1257-1265. doi: 10.1177/13524585231187289. Epub 2023 Aug 3.
4
Dietary factors and MRI metrics in early Multiple Sclerosis.饮食因素与早期多发性硬化症的 MRI 指标。
Mult Scler Relat Disord. 2021 Aug;53:103031. doi: 10.1016/j.msard.2021.103031. Epub 2021 May 19.
5
Sleep disturbance and memory dysfunction in early multiple sclerosis.早期多发性硬化症中的睡眠障碍和记忆功能障碍。
Ann Clin Transl Neurol. 2021 Jun;8(6):1172-1182. doi: 10.1002/acn3.51262. Epub 2021 May 5.
6
Contribution of Gray Matter Atrophy and White Matter Damage to Cognitive Impairment in Mildly Disabled Relapsing-Remitting Multiple Sclerosis Patients.轻度残疾复发缓解型多发性硬化症患者中灰质萎缩和白质损伤对认知障碍的影响
Diagnostics (Basel). 2021 Mar 23;11(3):578. doi: 10.3390/diagnostics11030578.
7
Thalamic Atrophy Predicts 5-Year Disability Progression in Multiple Sclerosis.丘脑萎缩可预测多发性硬化症患者5年的残疾进展情况。
Front Neurol. 2020 Jul 15;11:606. doi: 10.3389/fneur.2020.00606. eCollection 2020.
8
Reduced accuracy of MRI deep grey matter segmentation in multiple sclerosis: an evaluation of four automated methods against manual reference segmentations in a multi-center cohort.MRI 对多发性硬化症患者脑深部灰质结构分割准确性的影响：在多中心队列中对四种自动分割方法与手动参考分割进行比较。
J Neurol. 2020 Dec;267(12):3541-3554. doi: 10.1007/s00415-020-10023-1. Epub 2020 Jul 3.
9
Functional Connectivity Alterations Reveal Complex Mechanisms Based on Clinical and Radiological Status in Mild Relapsing Remitting Multiple Sclerosis.基于临床和影像学状态的功能连接改变揭示了轻度复发缓解型多发性硬化症的复杂机制。
Front Neurol. 2018 Aug 20;9:690. doi: 10.3389/fneur.2018.00690. eCollection 2018.