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一名患有沙丁胺醇诱发乳酸性酸中毒的哮喘患者出现心房颤动。

Atrial fibrillation in an asthmatic patient with albuterol-induced lactic acidosis.

作者信息

Reyes-Mondragon Alan, Delgado-García Guillermo, Pacheco-Cantú Adán, Contreras-Garza Nancy, Galarza-Delgado Dionicio Ángel, González-Aguirre Julio

出版信息

Pneumologia. 2016 Jul-Sep;65(3):150-1.

Abstract

Asthma is a highly prevalent chronic respiratory disease affecting millions of people worldwide. Short-acting beta 2-agonists induce bronchodilation and usually are prescribed as a rescue medication. They are recognized as a cause of hyperlactatemia and, less frequently, lactic acidosis. Short-acting beta 2-agonists are also known for their potentially adverse cardiovascular effects, such as atrial fibrillation. Differential diagnosis and subsequent treatment of the latter entity are important due to the adverse prognosis related to it. In this case report, we describe the unusual association between albuterol-induced lactic acidosis and atrial fibrillation in a patient with an asthma exacerbation.

摘要

哮喘是一种高度流行的慢性呼吸道疾病,影响着全球数百万人。短效β2激动剂可诱导支气管扩张,通常作为急救药物使用。它们被认为是高乳酸血症的一个病因,较少情况下会导致乳酸酸中毒。短效β2激动剂还因其潜在的心血管不良影响而闻名,如心房颤动。由于其相关的不良预后,对后者进行鉴别诊断和后续治疗很重要。在本病例报告中,我们描述了一名哮喘加重患者中沙丁胺醇诱导的乳酸酸中毒与心房颤动之间的不寻常关联。

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