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头颈部恶性雀斑样痣的治疗:加拿大安大略省的实践调查

Treatment for Lentigo Maligna of the Head and Neck: Survey of Practices in Ontario, Canada.

作者信息

Liu Annie, Botkin Alexis, Murray Christian, Goldstein David, Hofer Stefan O P, Solish Nowell, Kitchen Jessica, Chan An-Wen

机构信息

Division of Dermatology, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada.

Division of Otolaryngology, University Health Network, Toronto, Ontario, Canada.

出版信息

Dermatol Surg. 2018 Jul;44(7):918-923. doi: 10.1097/DSS.0000000000001498.

Abstract

BACKGROUND

Lentigo maligna is an in situ form of cutaneous melanoma that commonly arises on the head and neck. Various surgical and nonsurgical treatment options are available but no randomized trials exist to guide practice.

OBJECTIVE

To determine the current treatment practices for lentigo maligna of the head and neck in Ontario, Canada.

MATERIALS AND METHODS

Cross-sectional survey of dermatologists, plastic surgeons, and head and neck surgeons.

RESULTS

The response rate was 35% (190/542). Wide excision with immediate reconstruction was the most commonly recommended treatment for tumors on the cheek (69%), whereas staged excision with margin control was recommended most often for tumors on the nasal ala (60%). Overall, 5 mm was the most frequently recommended initial surgical margin (69%); 26.5% of respondents recommended margins wider than 5 mm. For tumors on the nasal ala, eyelid, and ear helix, more than 30% of respondents recommended an initial margin narrower than 5 mm.

CONCLUSION

Although surgical excision is the predominant treatment modality for lentigo maligna on the head and neck, practices vary considerably in terms of the type of excision and the initial margin used. Potential response bias and the geographic restriction of our sample may limit the generalizability of our results.

摘要

背景

恶性雀斑样痣是皮肤黑色素瘤的一种原位形式,常见于头颈部。有多种手术和非手术治疗选择,但尚无随机试验来指导实践。

目的

确定加拿大安大略省头颈部恶性雀斑样痣的当前治疗方法。

材料与方法

对皮肤科医生、整形外科医生以及头颈外科医生进行横断面调查。

结果

回复率为35%(190/542)。对于脸颊部肿瘤,最常推荐的治疗方法是广泛切除并立即重建(69%),而对于鼻翼部肿瘤,最常推荐的是分期切除并控制切缘(60%)。总体而言,最常推荐的初始手术切缘为5毫米(69%);26.5%的受访者推荐切缘宽度大于5毫米。对于鼻翼、眼睑和耳轮上的肿瘤,超过30%的受访者推荐初始切缘窄于5毫米。

结论

虽然手术切除是头颈部恶性雀斑样痣的主要治疗方式,但在切除类型和使用的初始切缘方面,做法差异很大。潜在的应答偏倚以及我们样本的地理局限性可能会限制我们结果的普遍性。

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