New York, N.Y. From the Memorial Sloan-Kettering Cancer Center.
Plast Reconstr Surg. 2012 Feb;129(2):288e-299e. doi: 10.1097/PRS.0b013e31823aeb72.
Melanoma of the lentigo maligna subtype presents diagnostic and treatment challenges because of ill-defined clinical margins in cosmetically and functionally sensitive areas of the head and neck with extensive sun damage. This review highlights the natural history, varied clinical presentations, and pitfalls in histologic diagnosis. The focus is on the surgical management, comparing excision and pathologic tissue processing techniques of wide excision, Mohs micrographic surgery, and staged excision. Staged excision is recommended for optimal surgical margin control. Nonsurgical treatment modalities are also reviewed for the elderly or unresectable cases.
恶性雀斑样痣型黑素瘤因其在头颈部广泛日晒损伤的美容和功能敏感区域具有界定不明确的临床边界而在诊断和治疗方面存在挑战。本文重点讨论了外科治疗，比较了广泛切除、Mohs 显微外科手术和分期切除的切除和病理组织处理技术。对于老年或不可切除的病例，也回顾了非手术治疗方法。
