Hückel C, Brock J
Allerg Immunol (Leipz). 1987;33(1):15-20.
Fc gamma R are glycoproteins or phospholipoproteins respectively. Their molecular weight depends on type and origin of the Fc gamma R-coated cell and was determined between 40 and 115 KD. Fc gamma R can be estimated by means of rosetting assay or binding experiments with isotopic or fluorescein labeled immune complexes or aggregated IgG respectively. Depending on the cell type Fc gamma R are involved in different reactions after respective binding of their ligands. A lot of results are described in the literature, indicating that Fc gamma R bearing T lymphocytes are suppressor cells in the humoral immune response, but generally accepted data about the involvement of Fc gamma R in this suppression do not exist. Some models are represented in this paper.
FcγR分别为糖蛋白或磷脂蛋白。其分子量取决于FcγR包被细胞的类型和来源，测定值在40至115千道尔顿之间。FcγR可分别通过玫瑰花环试验或与同位素或荧光素标记的免疫复合物或聚集的IgG进行结合实验来评估。根据细胞类型，FcγR在各自结合其配体后参与不同反应。文献中描述了许多结果，表明带有FcγR的T淋巴细胞在体液免疫反应中是抑制细胞，但关于FcγR参与这种抑制作用的普遍接受的数据并不存在。本文介绍了一些模型。
