儿茶酚胺和钙离子介导大鼠心脏磷酸果糖激酶活性及活性巯基增加。
Catecholamines and Ca2+ mediate an increase in activity and reactive thiols of rat heart phosphofructokinase.
作者信息
Clark M G, Rattigan S, Patten G S, Filsell O H
出版信息
Biochem J. 1987 Mar 1;242(2):597-601. doi: 10.1042/bj2420597.
Abstract
Catecholamines and Ca2+ mediate an increase in reactive-thiol status of phosphofructokinase, associated with an increase in activation of the enzyme. A correlation was observed between the number of reactive thiols and activation (r = 0.878; P less than 0.001) for 14 different treatments, with approx. 1 group per 85,000-Mr subunit becoming available over the range from the lowest to the highest state of activation.
摘要
儿茶酚胺和Ca2+介导磷酸果糖激酶反应性巯基状态的增加，这与该酶活性的增加相关。对于14种不同处理，观察到反应性巯基数量与活性之间存在相关性（r = 0.878；P小于0.001），在从最低到最高活性状态的范围内，每85,000-Mr亚基约有1个基团变得可用。
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