Giannos Aris, Stavrou Sofoklis, Gkali Christina, Chra Eleni, Marinopoulos Spyridon, Chalazonitis Athanasios, Dimitrakakis Constantine, Drakakis Peter
1st OB.GYN Department, School of Medicine, National and Kapodistrian University of Athens, Alexandra Hospital, Lourou and Vasilissis Sofias Ave, 11528 Athens, Greece.
Department of Radiology, Alexandra Hospital, Athens, Greece.
Int J Surg Case Rep. 2017 Nov 21;41:427-430. doi: 10.1016/j.ijscr.2017.11.026. eCollection 2017.
Giant juvenile fibroadenomas represent only the 0.5% of all fibroadenomas, constituting a rare condition in adolescence. In prepuberty, the presence of this condition is extremely rare.
We describe a rare case of a 12- year-old Caucasian girl who presented to our Hospital complaining of a palpable mass with rapid enlargement in her right breast that she had first noticed 3 months ago. Her menarche hadn't occurred yet.
Physical examination showed a giant mass of 15 × 13 cm in the right breast. The patient was further evaluated via ultrasonography showing a sole large lesion of 13 × 12 cm in the right breast. A surgical procedure under general anesthesia was performed. Histopathological findings after the surgical excision were suggestive of giant juvenile fibroadenoma. The patient has a normal breast development over a period of 9 month follow up.
Giant juvenile fibroadenomas should be included in differential diagnosis of a breast mass in prepubertal girls despite the fact that they are very rare in prepuberty, tend to appear later during adolescence and their prevalence is lower in Caucasians. The remarkable size and the rapid growth of the lesion should not be ruled out in the diagnostic process of an adolescent breast.
巨大型青少年纤维腺瘤仅占所有纤维腺瘤的0.5%,是青春期的一种罕见病症。在青春期前,这种病症极为罕见。
我们描述了一例罕见病例,一名12岁的白人女孩因右乳可触及肿块且迅速增大前来我院就诊,她3个月前首次发现该肿块。她尚未初潮。
体格检查显示右乳有一个15×13厘米的巨大肿块。通过超声进一步评估显示右乳有一个13×12厘米的单一较大病变。在全身麻醉下进行了手术。手术切除后的组织病理学结果提示为巨大型青少年纤维腺瘤。在9个月的随访期内,患者乳房发育正常。
尽管巨大型青少年纤维腺瘤在青春期前非常罕见,往往在青春期后期出现,且在白种人中患病率较低,但在青春期前女孩乳房肿块的鉴别诊断中应考虑到这种疾病。在青少年乳房的诊断过程中,不应排除病变的显著大小和快速生长。