Suppr超能文献

隐匿性滤泡状甲状腺癌表现为急性轻截瘫:一例报告

Acute paraparesis as presentation of an occult follicular thyroid carcinoma: A case report.

作者信息

Baião José Miguel, Guimarães Andreia, Moreira Nídia, Correia João Guardado, Rosenvinge Cristina Uriarte, Gonçalves Diana, Calvo Mercedes Agundez

机构信息

General Surgery Department, Instituto Português de Oncologia de Coimbra Francisco Gentil E.P.E, Av. Bissaya Barreto 98, 3000-075 Coimbra, Portugal.

General Surgery Department (C), Centro Hospitalar e Universitário de Coimbra (Hospital Geral-Covões), S. Martinho de Bispo, 3041-853 Coimbra, Portugal.

出版信息

Int J Surg Case Rep. 2017 Nov 28;41:498-501. doi: 10.1016/j.ijscr.2017.11.045. eCollection 2017.

Abstract

INTRODUCTION

Follicular thyroid carcinoma is the second most frequent type of well differentiated thyroid tumours. It is usually confined to the thyroid gland, however it can metastasize in a later stage of the disease. Signs and symptoms associated with bone metastasis are rare as first clinical manifestations.

CASE REPORT

An 84-year-old female complained with acute paraparesis. Magnetic resonance imaging revealed an extensive intraosseous infiltrating lesion compatible with a bone metastasis from an occult tumour. Biopsy samples were compatible with bone metastasis from a follicular thyroid carcinoma. The patient was submitted to total thyroidectomy followed by iodine ablative therapy.

DISCUSSION

Follicular thyroid carcinoma presentation with symptoms related to bone metastasis is rare. Patients with bone lesions, such as pathological fractures or compressive symptoms should be studied since they may have clinically unapparent lesions from an unknown tumour. Patients with FTC should be submitted to total thyroidectomy. Bone lesions may be addressed to improve quality of life however this decision depends on disease extent.

CONCLUSION

Acute paraparesis is a rare form of presentation of thyroid carcinoma. These neoplasms must be taken into account when investigating metastasis to the bone from unknown neoplasms.

摘要

引言

滤泡性甲状腺癌是分化良好的甲状腺肿瘤中第二常见的类型。它通常局限于甲状腺,但在疾病后期可能会发生转移。作为首发临床表现,与骨转移相关的体征和症状很少见。

病例报告

一名84岁女性因急性双下肢轻瘫就诊。磁共振成像显示广泛的骨内浸润性病变,与隐匿性肿瘤的骨转移相符。活检样本与滤泡性甲状腺癌的骨转移相符。患者接受了全甲状腺切除术,随后进行碘消融治疗。

讨论

滤泡性甲状腺癌以与骨转移相关的症状表现较为罕见。对于有骨病变的患者,如病理性骨折或压迫症状,应进行检查,因为他们可能患有临床上不明显的未知肿瘤病变。患有滤泡性甲状腺癌的患者应接受全甲状腺切除术。骨病变可根据情况进行处理以提高生活质量,但这一决定取决于疾病的范围。

结论

急性双下肢轻瘫是甲状腺癌一种罕见的表现形式。在调查不明肿瘤的骨转移时,必须考虑到这些肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e307/5723273/aa964c7960c2/gr1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验