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一例甲状腺胸内滤泡癌:一种罕见的表现。

An intra-thoracic follicular carcinoma of thyroid: An uncommon presentation.

作者信息

Kant Surya, Srivastava Anand, Kumar Rahul, Verma Ajay Kumar, Mishra Anand Kumar, Husain Nuzhat

机构信息

Department of Respiratory Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.

Department of Surgery, King George's Medical University, Lucknow, Uttar Pradesh, India.

出版信息

Lung India. 2017 Mar-Apr;34(2):193-196. doi: 10.4103/0970-2113.201293.

DOI:10.4103/0970-2113.201293
PMID:28360474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5351368/
Abstract

Follicular carcinoma of thyroid is the second most common type of carcinoma of thyroid, and it may metastasize to bone, lung, brain, and skin. However, the initial presentation of follicular carcinoma of the thyroid as a large intrathoracic mass without any symptoms of thyroid gland enlargement and dysfunction is very rare. We hereby report a case of a 50-year-old male who presented with chief complaints of chest and low back pain. Preliminary evaluation led to the provisional diagnosis of left-sided intrathoracic mass with vertebral metastasis which was suspected to be a case of bronchogenic carcinoma with distant metastasis. Surprisingly, transthoracic biopsy and histopathology revealed metastasis from follicular carcinoma of thyroid. This prompted us for a retrograde evaluation for a primary thyroid malignancy for which an ultrasound and contrast enhanced computed tomography (CECT) of the neck was done which confirmed the presence of a solitary thyroid nodule. Ultrasonography-guided fine-needle aspiration cytology of the nodule revealed follicular carcinoma of thyroid. Histopathological evaluation subsequent to total thyroidectomy revealed follicular carcinoma thyroid, further confirming the diagnosis. The patient was then referred to Department of Nuclear Medicine and Radiotherapy for radionuclide ablation and chemotherapy. We chose to report this case because of its rare presentation as a large intrathoracic mass and the retrograde diagnosis of follicular carcinoma of thyroid. To the best of our knowledge, this is the first report of such a rare case.

摘要

甲状腺滤泡癌是甲状腺癌的第二常见类型,它可能转移至骨骼、肺、脑和皮肤。然而,甲状腺滤泡癌最初表现为巨大的胸腔内肿块,而无任何甲状腺肿大及功能障碍症状的情况非常罕见。我们在此报告一例50岁男性,其主要症状为胸痛和腰痛。初步评估导致初步诊断为左侧胸腔内肿块伴椎体转移,怀疑是一例伴有远处转移的支气管源性癌。令人惊讶的是,经胸活检和组织病理学检查显示为甲状腺滤泡癌转移。这促使我们对原发性甲状腺恶性肿瘤进行追溯评估,为此进行了颈部超声和增强计算机断层扫描(CECT),证实存在一个孤立的甲状腺结节。结节的超声引导下细针穿刺细胞学检查显示为甲状腺滤泡癌。全甲状腺切除术后的组织病理学评估显示为甲状腺滤泡癌,进一步证实了诊断。然后该患者被转诊至核医学与放疗科进行放射性核素消融和化疗。我们选择报告该病例是因为其罕见地表现为巨大的胸腔内肿块以及甲状腺滤泡癌的追溯诊断。据我们所知,这是此类罕见病例的首例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e5/5351368/6cc809c0adc8/LI-34-193-g008.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e5/5351368/45de5ac91f6e/LI-34-193-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e5/5351368/6cc809c0adc8/LI-34-193-g008.jpg

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本文引用的文献

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Unusual presentation of follicular carcinoma thyroid with special emphasis on their management.甲状腺滤泡癌的不寻常表现,特别强调其治疗。
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Brain metastasis from papillary carcinoma of thyroid gland.甲状腺乳头状癌脑转移
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