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[C57BL/Ka小鼠中胸腺再植能力与辐射诱导的白血病前期细胞形成淋巴瘤之间的关系]

[Relations between the capacity of thymic repeopling and the formation of lymphoma obtained by radiation-induced preleukemic cells in C57BL/Ka mice].

作者信息

Rongy A M, Defresne M P, Greimers R, Humblet C, Boniver J

出版信息

C R Seances Soc Biol Fil. 1987;181(1):88-93.

PMID:2954627
Abstract

We have analyzed the repopulation of thymuses injected with preleukemic cells obtained at various interval after fractionated irradiation. Our results show that preleukemic cells can repopulate the thymus transiently as normal thymocytes or they can proliferate in recipients. In all cases, preleukemic cells can give rise to donor lymphomas.

摘要

我们分析了在分次照射后的不同时间间隔获取的白血病前期细胞注射入胸腺后的再增殖情况。我们的结果表明,白血病前期细胞能够作为正常胸腺细胞短暂地在胸腺中再增殖,或者它们能够在受体中增殖。在所有情况下,白血病前期细胞都能引发供体淋巴瘤。

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