Smith P Alex, Wang Yaxin, Metcalfe Ralph W, Sampaio Luiz C, Timms Daniel L, Cohn William E, Frazier O H
1 Texas Heart Institute, Houston, TX, USA.
2 University of Houston, Houston, TX, USA.
Int J Artif Organs. 2018 Mar;41(3):144-151. doi: 10.1177/0391398817752291. Epub 2018 Feb 11.
A minimally invasive, partial-assist, intra-atrial blood pump has been proposed, which would unload the left ventricle with a flow path from the left atrium to the arterial system. Flow modulation is a common strategy for ensuring washout in the pump, but it can increase power consumption because it is typically achieved through motor-speed variation. However, if a pump's performance curve had the proper gradient, flow modulation could be realized passively. To achieve this goal, we propose a pump performance operating curve as an alternative to the more standard operating point.
Mean-line theory was employed to generate an initial set of geometries that were then tested on a hydraulic test rig at ~20,000 r/min. Experimental results show that the intra-atrial blood pump performed below the operating region; however, it was determined that smaller hub diameter and longer chord length bring the performance of the intra-atrial blood pump device closer to the operating curve.
We found that it is possible to shape the pump performance curve for specifically targeted gradients over the operating region through geometric variations inside the pump.